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Sulfo-NHS (N-Hydroxysulfosuccinimide sodium salt), Pierce™

Supplier: Paul Schöndorf Metallwaren GmbH
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24510 24525
PI24510EA 305.63 USD InStock
PI24510 PI24525
Sulfo-NHS (N-Hydroxysulfosuccinimide sodium salt), Pierce™
Sulfo-NHS (N-Hydroxysulfosuccinimide sodium salt)
Pierce™ Sulfo-NHS (N-hydroxysulfosuccinimide) is a chemical modification reagent for converting carboxyl groups to amine-reactive NHS esters for bioconjugation, crosslinking, labeling and immobilization methods.

  • Improve efficiency of EDC coupling reactions
  • Water-soluble and membrane-impermable
  • Activate nanoparticles with amine-reactive Sulpho-NHS esters
  • Crosslink proteins to carboxyl-coated beads or surfaces more efficiently

Sulfo-NHS (N-hydroxysulfosuccinimide) enables control and modification of carbodiimide crosslinking reactions involving activation of carboxylates (—COOH) for conjugation with primary amines (—NH2). Derivatives are easily synthesized by mixing the Sulfo-NHS with a carboxyl-containing molecule and a dehydrating agent such as the carbodiimide EDC (EDAC). The method is the basis for generating many types of protein labeling reagents, including amine-reactive fluorescent dyes, biotin affinity tags and pegylation compounds.

Precaución: For Research Use Only. Not for use in diagnostic procedures.


Formula: C₄H₄NNaO₆S
MW: 217.13 g/mol
 MDL Number: MFCD00043100
CAS Number: 106627-54-7
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Specification Test Results
Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Carbodiimide
Spacer Short
Form Powder
Quantity 500 mg
Type Crosslinker
Solubility Water

 

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