AG-CN2-0087-M001
AG-CN2-0087-M005
102987-298EA
83.08
USD
InStock
102987-298
102987-300
Apicidin ≥98% (by HPLC, TLC)
Apicidin
Antiprotozoal. Potent inhibitor of histone deacetylase (HDAC). Inhibits proliferation. Induces cell cycle arrest at the G1 phase. Induces hyperacetylation of histone H4. Apoptosis inducer. Potent anti-angiogenic compound. Decreases HIF-1alpha protein levels and transcriptional activity in human and mouse tumor cell lines. Autophagy inducer in oral squamous cell carcinoma (OSCC) cells. Promotes either self-renewal or differentiation of embryonic stem cells.