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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Lactacystin ≥98%

Supplier: Van Der Voort Lucht en Milieu Amste

AG-CN2-0104-C100 AG-CN2-0104-C200 AG-CN2-0104-C500 AG-CN2-0104-M001
102987-354EA 96.92 USD InStock
102987-354 102987-356 102987-358 102987-360
Lactacystin ≥98%
Lactacystin
Induces neuritogenesis. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP; multicatalytic complex). Blocks proteasome activity by targeting the catalytic beta-subunit. Apoptosis inducer. Anticancer compound. Upregulates HSP70 and HSP22. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Inhibits NF-kappaB activation by inhibiting IkappaB degradation. Cathepsin A inhibitor. beta-Secretase activity inhibitor. Anti-adipogenic. Autophagy inducer.


Formula: C₁₅H₂₄N₂O₇S
MW: 376.4 g/mol
Storage Temperature: Freezer
 CAS Number: 133343-34-7
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Specification Test Results
Source/Host Isolated from Streptomyces lactacystinnaeus strain OM-6519.
Purity 98% (HPLC)
Appearance/Color White to off-white solid.
Solubility Soluble in water, methanol, ethanol, DMSO, pyridine, acetonitrile or dimethyl formamide. Insoluble in hexane, benzene, chloroform or ethyl acetate.

 

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