AG-CR1-0087-M001
AG-CR1-0087-M005
102988-540EA
96.92
USD
InStock
102988-540
102988-542
LY-333,531 hydrochloride ≥98% (by HPLC)
LY-333,531 hydrochloride
Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta). PKCbetaI and PKCbetaII isozyme inhibitor. Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy. Anti-cancer and anti-angiogenic compound. Suppresses glucose-induced adhesion of human monocytes to endothelial cells. Suppresses ERK1/2 and Akt phosphorylation.