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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Ruxolitinib ≥98%

Supplier: Van Der Voort Lucht en Milieu Amste
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AG-CR1-3624-M005 AG-CR1-3624-M025
102988-810EA 90 USD InStock
102988-810 102988-812
Ruxolitinib ≥98%
Ruxolitinib
Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and psoriasis. Anticancer agent. Shown to induce apoptosis and autophagy. Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro.


Formula: C₁₇H₁₈N₆
MW: 306.4 g/mol
Storage Temperature: Freezer
 MDL Number: MFCD12031592
CAS Number: 941678-49-5
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Specification Test Results
Purity >98% (HPLC)
Appearance/Color White to off-white solid.
Solubility Soluble in DMSO or ethanol. Insoluble in water.

 

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