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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

N-Dodecanoyl-DL-homoserine lactone ≥97%

Supplier: Van Der Voort Lucht en Milieu Amste

CDX-D0339-M010 CDX-D0339-M050
102989-800EA 123.23 USD InStock
102989-800 102989-802
N-Dodecanoyl-DL-homoserine lactone ≥97%
N-Dodecanoyl-DL-homoserine lactone
N-Dodecanoyl-DL-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It also was shown to induce cell death by apoptosis.


Formula: C₁₆H₂₉NO₃
MW: 283.4 g/mol
Storage Temperature: Refrigerator
 MDL Number: MFCD03100412
CAS Number: 18627-38-8
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Specification Test Results
Source/Host Synthetic.
Purity 97% (GC)
Appearance/Color White solid.
Solubility Soluble in chloroform.

 

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