SYN-1026-M001
SYN-1026-M005
SYN-1026-M010
SYN-1026-M050
102991-446EA
96.92
USD
InStock
102991-446
102991-448
102991-450
102991-452
BX-795 ≥95%
BX-795
BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC(50) 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-epsilon. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of interferon regulatory factor 3. BX795 also is a potent inhibitor of cell growth of multiple cancer cell lines with IC(50) values ranging from submicromolar amounts (0.368µM to greater than 450µM.