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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Momelotinib ≥95%

Supplier: Van Der Voort Lucht en Milieu Amste

SYN-1035-M001 SYN-1035-M005 SYN-1035-M010 SYN-1035-M050
102991-518EA 119.08 USD InStock
102991-518 102991-520 102991-522 102991-524
Momelotinib ≥95%
Momelotinib
CYT387 is selective inhibitor of JAK1 and JAK2 kinases including the JAK2V617F mutant . Using ATP kinase assays IC(50) values for JAK1 (11nm), JAK2, (18nM), JAK2, JAK2V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC(50) 100nM) detected against CDK2/cyclin A, MAPK8 (JNK1), PRKCN (PKD3), PRKD1 (PKCµ), ROCK2, and TBK1 kinase as well.


Formula: C₂₃H₂₂N₆O₂
MW: 414.5 g/mol
Storage Temperature: Freezer
 MDL Number: MFCD16038899
CAS Number: 1056634-68-4
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Specification Test Results
Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO.

 

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