SYN-1045-M001
SYN-1045-M005
SYN-1045-M010
SYN-1045-M050
102991-598EA
90
USD
InStock
102991-598
102991-600
102991-602
102991-604
IC87114 ≥95%
IC87114
IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10µM to 200µM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression.