SYN-1077-M001
SYN-1077-M005
SYN-1077-M010
SYN-1077-M050
102991-862EA
119.08
USD
InStock
102991-862
102991-864
102991-866
102991-868
SB590885 ≥95%
SB590885
SB-590885 is a novel, potent and selective small molecule inhibitor of B-Raf kinase, with a Ki of 0.16nM. It shows an 11-fold greater selectivity for B-Raf over c-Raf. It was used to address the dependence of MAPK signalling and tumor cell growth on B-Raf kinase activity.