SYN-1080-M001
SYN-1080-M005
SYN-1080-M010
SYN-1080-M050
102991-884EA
96.92
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102991-884
102991-886
102991-888
102991-890
BMS-387032 hydrochloride ≥95%
BMS-387032 hydrochloride
BMS387032 is a novel cyclin-dependent kinase inhibitor, which exhibits potent and selective inhibitory activity against Cdk2, Cdk7, and Cdk9. It inhibits CDK2 with an IC(50) of 48nM and up to 20-fold selective over CDK1/CDK4. It also inhibits CDK7/9 with IC(50) values of 62nM and 4nM. It has little effect on CDK6.