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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Baricitinib phosphate salt ≥95%

Supplier: Van Der Voort Lucht en Milieu Amste

SYN-1117-M001 SYN-1117-M005 SYN-1117-M010 SYN-1117-M050
102992-154EA 246.46 USD InStock
102992-154 102992-156 102992-158 102992-160
Baricitinib phosphate salt ≥95%
Baricitinib phosphate salt
Baricitinib is a selective JAK1 and JAK2 inhibitor. IC(50) values are 5.9nm for JAK1, and 5.7nM for JAK2. In cell based assays Baricitinib/INCB-28050 demonstrated inhibition of intracellular signaling of multiple pro-inflammatory cytokines including IL-6 and IL-23 at concentrations of 50nM, and also showed good efficacy in a number of animal models at doses of 10mg/kg and below. Baricitinib is in Phase III development as a potential treatment for rheumatoid arthritis. It is in Phase II development as a potential treatment for psoriasis and diabetic nephropathy


Formula: C₁₆H₁₇N₇O₂S·H₃PO₄
MW: 469.4 g/mol
Storage Temperature: Freezer
 MDL Number: MFCD25976707
CAS Number: 1187595-84-1
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Specification Test Results
Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO or ethanol.

 

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