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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

SGX-523 ≥95%

Supplier: Van Der Voort Lucht en Milieu Amste
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SYN-1155-M001 SYN-1155-M005 SYN-1155-M010 SYN-1155-M050
102992-418EA 149.54 USD InStock
102992-418 102992-420 102992-422 102992-424
SGX-523 ≥95%
SGX-523
SGX523 is an ATP-competitive, triazolopyridazine-based inhibitor of MET at an IC(50) of 4nM. SGX523 has higher affinity for the unphosphorylated form of MET (Ki = 2.7nM) than the more active phospho-enzyme (Ki = 23nM). In a broad panel of 213 kinases, SGX523 was extremely selective, with no inhibition >36%, suggesting IC(50) values > 1µM, including the closely-associated RON kinase.


Formula: C₁₈H₁₃N₇S
Storage Temperature: Freezer
 MDL Number: MFCD16660190
CAS Number: 1022150-57-7
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Specification Test Results
Purity >95%
Appearance/Color Solid.
Solubility Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.

 

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