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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

AZD-26 ≥95%

Supplier: Van Der Voort Lucht en Milieu Amste

SYN-1160-M001 SYN-1160-M005 SYN-1160-M010
102992-456EA 292.15 USD InStock
102992-456 102992-458 102992-460
AZD-26 ≥95%
AZD-26
AZD-26 is an inhibitor of AKT. AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with an IC(50) of 422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with an IC(50) of 322nM. AZD-26 inhibited AKT mediated phosphorylation at ranges form 0.01µM to 10µM after 24 hour exposure in several rat and human cell models. Likewise AZD-25 used at 100-200mg/kg also inhibited AKT phosphorylation and subsequent activation.


Formula: C₂₂H₂₁N₃O
MW: 343.4 g/mol
Storage Temperature: Freezer
 CAS Number: 1357158-81-6
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Specification Test Results
Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO or ethanol.

 

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