SYN-1208-M001
SYN-1208-M005
SYN-1208-M010
102992-798EA
224.31
USD
InStock
102992-798
102992-800
102992-802
TASP0415914 ≥95%
TASP0415914
PI3Kgamma is required for for T-cell and B-cell as well as mast cell migration and degranulation. As such, these kinases are attractive targets for potential anti-infmamatory drugs. TASP0415914 has shown excellent results in cell based assays. It is orally available and has performed will in murine in vivo models. PI3Kgamma IC(50) 29nM, AKT IC(50) 294nM.