850306P1G
850306P500MG
850306P200MG
850306P25MG
100126-872EA
959.54
USD
InStock
100126-872
100128-628
100122-252
100124-676
1,2-Diheptanoyl-sn-glycero-3-phosphocholine ≥99%, powder
1,2-Diheptanoyl-sn-glycero-3-phosphocholine
DHPC preserves the native conformation and therefore the activity of the solubilized proteins. The three dimensional structure and activity of proteins are retained not only at the 10-15mM DHPC concentrations at which maximum solubilization usually occurs, but also over a large range of DHPC concentrations (up to 40mM).
- Purified by HPLC
- Special precautions are taken to protect the products for oxidization and hydrolysis
Not only is the three dimensional structure and hence the activity of most protein retained in excess DHPC, but the proteins also appear to be stable in DHPC. Such a result suggests that the direct interaction of DHPC with integral membrane proteins is weak. If the interaction of DHPC with membrane proteins is indeed weak, it follows that intrinsic membrane lipids will remain associated with the membrane proteins.