0215111980
0215111990
76102-706EA
128.58
USD
InStock
76102-706
76102-708
Ferritin (equine from horse spleen, thick), dark brown liquid
Ferritin
Ferritin, Equine is a shell of 24 protein subunits (apoferritin) and a core Fe 3+ ions with a peptide MW of 440 kDa. Review of the ferritin-like superfamily of iron-storage proteins, virtually ubiquitous in life on earth.
A ubiquitous iron storage protein that plays a key role in iron metabolism. It serves as an intracellular iron reserve (particularly in spleen, liver, intestinal mucosa, and bone marrow) and functions in iron detoxification. Studies have shown that ferritin iron incorporation is mediated by a ferroxidase activity associated with ferritin H subunits and a nucleation center associated with ferritin L subunits. Release of iron from ferritin has an essential role in iron-dependent lipid peroxidation and may contribute to free radical-induced cell damage in vivo. Therefore, by binding iron, ferritin may function as an antioxidant.
Store at +4 °C.
- Presentation: Thick, Dark Brown Liquid
- Formulation: In 150 mM NaCl, 0.002% sodium azide
- 2X Crystallized, Essentially cadmium-free, but may contain up to 1% (as % of ferritin)
- Soluble in 0.15 M sodium chloride, distilled water or dilute buffer