0219486891
0219486890
76177-248EA
112.41
USD
InStock
76177-248
76177-320
tri-Sodium citrate dihydrate
tri-Sodium citrate dihydrate
Citric acid is a key metabolic intermediate. Citrate is the starting point of the tricarboxylic acid cycle. Its concentration also coordinates several other metabolic pathways. Citric acid can form complexes with various cations, particularly with iron and calcium. In animals, citric acid improves the utilization of nutritional calcium. Citric acid is produced commercially by fermentation of carbohydrates derived from corn starch and from beet molasses.
Citric Acid, Trisodium Salt, Dihydrate is used as a substrate for citrate lyase, a buffer component; an anticoagulant. For anticoagulation use it is typically used at a concentration of approximately 0.129 M (i.e. for 4.5 mL blood use 16.0 mg sodium citrate and 2.1 mg citric acid).
To make a sodium citrate buffer use equimolar concentrations (typically approximately 0.05 M concentration) of citric acid, free acid and sodium citrate. Add equal volumes of each solution and titrate to the desired pH.
Room Temperature
- ACS Grade
- Presentation: White Powder
- Freely soluble in water (> 100 mg/mL - clear, colorless solution). pH of a 0.1 M solution in water is approximately 7.5 to 9.0; Insoluble in alcohol.