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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Ribavirin

Supplier: E. Becker & Co. GmbH
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0219606650 0219606610
76177-334EA 199.28 USD InStock
76177-334 76177-488
Ribavirin
Ribavirin
Ribavarin is an antiviral compound reported to be active against RSV, HIV, HCV and other infectious agents. Its metabolite, ribavirin 5'-phosphate, inhibits inosine monophosphate dehydrogenase (IMP). It is also an analog of the imidazole nucleotide intermediates in purine nucleotide biosynthesis.
Ribavirin is active against a number of DNA and RNA viruses. It is a member of the nucleoside antimetabolite drugs that interfere with duplication of viral genetic material.
Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase, but many other mechanisms of action are also supported with experimental evidence.
Antiviral agent whose metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase. Used to inhibit purine (GTP pools) biosynthesis at the level of inosine monophosphate (IMP) dehydrogenase and as a precursor to the di- and tri-phosphates which inhibit viral RNA-dependent RNA polymerases.
Store at +4 °C.

  • Presentation: White Powder
  • Soluble in water (20 mg/mL - clear, colorless solution).


Formula: C8H12N4O5
Melting Pt: 173 °C (lit.)
Storage Temperature: Refrigerator
 MDL Number: MFCD00058564
CAS Number: 36791-04-5
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Specification Test Results
Identity Test Passes
Purity ≥99%
Specific Rotation Between -33.5° and -37.0°
pH 4.0-6.5
Loss on Drying ≤0.5%
Residue on Ignition ≤0.25%
Heavy Metals ≤0.001%
Chromatographic Purity Individual Peak ≤0.25%

 

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