EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride) Crosslinker
Supplier: G-BIOSCIENCES
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Danger
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BC25-5
BC25-1
BC25-50
95029-294EA
103.42
USD
95029-294
82021-610
76285-476
EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride) Crosslinker
EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride)
EDC is a heterobifunctional, water-soluble, zero-length carbodiimide crosslinker that is used to couple carboxyl groups to primary amines. EDC activates carboxyl groups first and forms amine reactive O-acylisourea imtermediate that spontaneously reacts with primary amines to form an amide bond and isourea by-product.
The unstable nature of the intermediate in aqueous solutions makes 2-step coupling, however in conjunction with N-hydroxysuccinimide, a 2-step coupling is possible.
EDC is ideal for peptide immobilization and hapten-carrier protein conjugation
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Formula:
C₈H₁₇N₃·HCl MW: 191.7 g/mol Melting Pt: ∼ 113 °C Storage Temperature: Refrigerator |
MDL Number:
MFCD00012503 CAS Number: 25952-53-8 EINECS: 247-361-2 UN: 2811 ADR: 6.1 II |