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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Tris(hydroxymethyl)aminomethane (TRIS, Trometamol), EMPROVE® JPC, USP, Ph. Eur., BP, SAFC®

Supplier: EMD MILLIPORE - PCS - GPS

1.08386.5000 1.08386.9025
EM1.08386.5000CS 7978.03 USD InStock
EM1.08386.5000 EM1.08386.9025
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol), EMPROVE® JPC, USP, Ph. Eur., BP, SAFC®
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol)
Hygroscopic. Endotoxin tested. Filtered through a 0.45µm element. Soluble in water. Toxic effects.

Hygroscopic. Endotoxin tested. Filtered through a 0.45 µm element. Soluble in water. Toxic effects.


Formula: NH₂C(CH₂OH)₃
MW: 121.14 g/mol
Boiling Pt: 357
Melting Pt: 169…172 °C
Density: 1.328 g/cm³ (20 °C)
Storage Temperature: Ambient
 MDL Number: MFCD00004679
CAS Number: 77-86-1
EINECS: 201-064-4
Merck Index: 13,09842
https://qa.digitalassets.avantorsciences.com/adaptivemedia/rendition?id=11a03d1ab6b2c11b9a2c83f0a73fc4264cec0110&vid=b84ca1743f9dfe50eb47c249460ab41a6772ceb2&prid=web&clid=SAPDAM
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Specification Test Results
Assay (acidimetric; calculated on dried substance) 99.0-100.5%
Appearance of solution (5%, water) Passes test
Arsenic (As) 0.00002% max
Chloride (Cl) 0.001% max
Colony count, aerobic bacteria 100CFU/g max
Colony count, yeast and mold 100CFU/g max
Endotoxins 0.03I.U./mg max
Escherichia coli Absent in 10 g
Filtration test (0.45 µm) Conforms
Heavy metals (as Pb) 0.0010% max
Identification A Passes test
Identification B Passes test
Identification C Passes test
Iron (Fe) 0.0010% max
Loss on drying (105°C) 0.5% max
Melting point 168-172°C
Organic volatile impurities (USP/NF) Conforms
Other Residual Solvents (Ph.Eur./ICH) Excluded by production process
pH (5%, water) 10.0-11.5
pH of a 1% aqueous solution 10.3-10.7
Pseudomonas Aeruginosa Absent in 10 g
Related substances (TLC) Conforms
Residual solvents (Ph.Eur./ICH) class 3 0.5% max
Salmonella Absent in 10 g
Staphylococcus Aureus Absent in 10 g
Sulfate (SO4) 0.005% max
Sulfated ash 0.1% max

 

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