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Photoreactive Cross Linkers, G-Biosciences

Supplier: G-BIOSCIENCES
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BC38 BC32 BC29 BC39 BC35 BC28 BC30 BC33 BC34
82022-840EA 709.46 USD InStock
82022-840 82022-828 82022-822 82022-842 82022-834 82022-820 82022-824 82022-830 82022-833
Photoreactive Cross Linkers, G-Biosciences
Chromatography Sorbents SPE Sorbents
G-Biosciences’ cross-linking agents contain at least two reactive groups that are reactive towards numerous groups, including sulfhydryls, amines and carbohydrates, and create chemical covalent bonds between two or more molecules. Functional groups that can be targeted with cross-linking agents are primary amines, carboxyls, sulfhydryls, carbohydrates and carboxylic acids. Protein molecules have many of these functional groups and therefore proteins and peptides can be readily conjugated using cross-linking agents.

G-Biosciences’ cross-linking agents are used for the following applications: protein structural and functional studies, cell membrane structural studies, protein & receptor interactions, cell surface studies, solid-phase immobilization, preparation of immunogens, immunotoxins and other conjugated protein reagents, protein to DNA/RNA cross-linking, reactive group transfer, protein-protein conjugation, and for immunological tools.

To select a cross-linking reagent several factors need to be considered (see selection guide). These factors include: Reactive Toward: determines the target residues to be cross-linked (select a reagent that does not interfere with protein function); Membrane Permeability: for cell surface labeling, select non-membrane permeable reagents; Cleavable: for easy release of cross-linked proteins from solid supports or for further downstream applications; Reversible: an alternative to cleavable reagents; Steric Hinderance: bulky groups around the binding site may require reagents with longer spacer arms.

G-Biosciences offers a variety of cross-linking agents, reaction specific buffers and accessories for performing and facilitating cross-linking applications. G-Biosciences’ cross-linking agents are divided into groups dependent on the number and similarity of the reactive groups. Photoreactive groups are used when no specific groups are available to react with as photoreactive groups react non-specifically upon exposure to UV light.

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Thank you for visiting our site. These terms and conditions of use are applicable to the United States, Canada and Puerto Rico websites (“collectively the Web Site”) operated by VWR (the “Company”). If you are accessing the Web Site from outside the United States, Canada, or Puerto Rico, please see the appropriate international website, available at www.vwr.com, for applicable terms and conditions. All users of the Web Site are subject to the following website terms and conditions of use (these “Terms of Use”). Please read these Terms of Use carefully before accessing or using any part of the Web Site. By accessing or using the Web Site, you agree that you have read, understand and agree to be bound by these Terms of Use, as amended from time to time, as well as the Company Privacy Policy, which is hereby incorporated into these Terms of Use. If you do not wish to agree to these Terms of Use, do not access or use any part of the Web Site.

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We respect the intellectual property of others, and we ask our users to do the same. If you believe that your work has been copied and is accessible on the Site in a way that constitutes copyright infringement, you may notify us by providing our copyright agent the following information:

  • an electronic or physical signature of the person authorized to act on behalf of the owner of the copyright interest;
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Our agent for notice of claims of copyright infringement on the Site can be reached at: solutions@vwr.com.

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