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(3,5-Difluorophenyl)(1-piperazinyl)methanone
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(3,5-Difluorophenyl)(1-piperazinyl)methanone
Catalog Number:
(76083-410)
Supplier:
Bioss
Description:
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.
Catalog Number:
(76237-148)
Supplier:
Rockland Immunochemical
Description:
Human Interleukin-12(p70) AccuSignal ELISA Kit
Catalog Number:
(103359-590)
Supplier:
Novus Biologicals
Description:
The TRAIL / TNFSF10 Antibody (55B709.3) from Novus Biologicals is a mouse monoclonal antibody to TRAIL / TNFSF10. This antibody reacts with human. The TRAIL / TNFSF10 Antibody (55B709.3) has been validated for the following applications: Western Blot, Immunohistochemistry-Paraffin.
Supplier:
Labconco
Description:
PuriCare Open Access Stations offer the utmost efficiency for cage changing operations
Supplier:
Restek
Description:
MXT®-Q-BOND columns are constructed from rugged material to withstand jostling and deliver robust performance.
Catalog Number:
(103321-852)
Supplier:
Novus Biologicals
Description:
The Annexin A3 Antibody (1E2.) from Novus Biologicals is a mouse monoclonal antibody to Annexin A3. This antibody reacts with human. The Annexin A3 Antibody (1E2.) has been validated for the following applications: Western Blot, ELISA, Immunoprecipitation.
Supplier:
PORTWEST LLC.
Description:
Our high-quality hi-vis two-tone zipped hoody has a oversize front contrast panel for protection against dirt.
Catalog Number:
(102993-504)
Supplier:
Eagle Biosciences
Description:
Mouse Interleukin 5 (IL-5) ELISA detects IL-5 concentrations in biological samples.
Supplier:
TCI America
Description:
CAS Number: 18281-04-4
MDL Number: MFCD00026690 Molecular Formula: C21H42O2 Molecular Weight: 326.57 Purity/Analysis Method: >96.0% (GC) Form: Crystal Freezing point (°C): 35
Catalog Number:
(102993-502)
Supplier:
Eagle Biosciences
Description:
Swine IL-4 ELISA detects Swine IL-4 concentrations in cell culture supernates, serum, and plasma.
Supplier:
Biotium
Description:
This antibody recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3). Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. MUC3 is distributed in colon and rectum, and is also present to a lesser extent in breast, lung and salivary gland tissues. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.
Supplier:
MP Biomedicals
Description:
Zinc arbonate is a mineral ore of zinc.
Catalog Number:
(102994-702)
Supplier:
Eagle Biosciences
Description:
Mouse Interleukin 10 ELISA detects mouse IL-10 concentrations in various samples.
Catalog Number:
(103279-556)
Supplier:
Novus Biologicals
Description:
The GNG13 Antibody from Novus Biologicals is a rabbit polyclonal antibody to GNG13. This antibody reacts with human. The GNG13 Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.
Catalog Number:
(75931-990)
Supplier:
Rockland Immunochemical
Description:
The solute carrier family SLC35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The novel protein SLC35D3 is highly homologous to SLC35D1 and SLC35D2, both of which transport UDP-glucuronic acid and UDP-N-acetylgalactosamine, suggesting that SLC35D3 is also involved in the transport of nucleotide sugars. It has been suggested that SLC35D3 regulates platelet dense granules, lysosome-related organelles which contain high concentrations of several biologically important low molecular weight molecules necessary for normal blood homeostasis.
Supplier:
TrippNT
Description:
Large bench, cabinet or instrument carts made from chemically resistant high density polyethylene for the demanding hospital and laboratory environment.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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