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[3-(1H-Imidazol-2-yl)propyl]amine+dihydrochloride
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[3-(1H-Imidazol-2-yl)propyl]amine+dihydrochloride
Catalog Number:
(77518-772)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human CTNNa1 (Catenin Alpha 1) ELISA Kit
Catalog Number:
(77523-116)
Supplier:
AFG BIOSCIENCE LLC
Description:
Rat ITGa2 (Integrin Alpha 2) ELISA Kit
Catalog Number:
(77519-822)
Supplier:
AFG BIOSCIENCE LLC
Description:
Rat LAMa1 (Laminin Alpha 1) ELISA Kit
Catalog Number:
(77514-738)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human ACTN2 (Actinin Alpha 2) ELISA Kit
Catalog Number:
(77517-466)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human ITGa6 (Integrin Alpha 6) ELISA Kit
Catalog Number:
(102126-050)
Supplier:
Novus Biologicals
Description:
Mouse Monoclonal GSK3 alpha Antibody (6G12C2). Tested Applications: Western Blot, ELISA. Tested Reactivity: Human.
Catalog Number:
(102120-964)
Supplier:
Novus Biologicals
Description:
The alpha-2C Adrenergic R / ADRA2C Antibody from Novus Biologicals is a rabbit polyclonal antibody to alpha-2C Adrenergic R / ADRA2C. This antibody reacts with human, mouse, rat. The alpha-2C Adrenergic R / ADRA2C Antibody has been validated for the following applications: Western Blot, Immunohistochemistry.
Catalog Number:
(10348-234)
Supplier:
Bioss
Description:
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. Negatively regulates the pathway by phosphorylating the scaffold protein TAXBP1 and thus promoting the assembly of the A20/TNFAIP3 ubiquitin-editing complex (composed of A20/TNFAIP3, TAX1BP1, and the E3 ligases ITCH and RNF11). Therefore, CHUK plays a key role in the negative feedback of NF-kappa-B canonical signaling to limit inflammatory gene activation. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. In turn, these complexes regulate genes encoding molecules involved in B-cell survival and lymphoid organogenesis. Participates also in the negative feedback of the non-canonical NF-kappa-B signaling pathway by phosphorylating and destabilizing MAP3K14/NIK. Within the nucleus, phosphorylates CREBBP and consequently increases both its transcriptional and histone acetyltransferase activities. Modulates chromatin accessibility at NF-kappa-B-responsive promoters by phosphorylating histones H3 at 'Ser-10' that are subsequently acetylated at 'Lys-14' by CREBBP. Additionally, phosphorylates the CREBBP-interacting protein NCOA3.
Catalog Number:
(77518-184)
Supplier:
AFG BIOSCIENCE LLC
Description:
Mouse aEP (Alpha-Endorphin) ELISA Kit
Catalog Number:
(77524-136)
Supplier:
AFG BIOSCIENCE LLC
Description:
Mouse LAMa5 (Laminin Alpha 5) ELISA Kit
Catalog Number:
(ABCA_AB229432-1X96)
Supplier:
ABCAM INC.
Description:
Human Interferon alpha 1 ELISA Kit, Fluorescent
Catalog Number:
(ABCA_AB100530-1X96)
Supplier:
ABCAM INC.
Description:
Human CXCL1 ELISA Kit (GRO alpha)
Catalog Number:
(ABCA_AB314383-1X96)
Supplier:
ABCAM INC.
Description:
Human S100 alpha 2/S100A2 ELISA Kit
Supplier:
Thermo Scientific Chemicals
Description:
a-Bromo-4-fluorophenylacetic acid, 96%
Catalog Number:
(10281-770)
Supplier:
Bioss
Description:
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
Catalog Number:
(10352-328)
Supplier:
Bioss
Description:
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. Negatively regulates the pathway by phosphorylating the scaffold protein TAXBP1 and thus promoting the assembly of the A20/TNFAIP3 ubiquitin-editing complex (composed of A20/TNFAIP3, TAX1BP1, and the E3 ligases ITCH and RNF11). Therefore, CHUK plays a key role in the negative feedback of NF-kappa-B canonical signaling to limit inflammatory gene activation. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. In turn, these complexes regulate genes encoding molecules involved in B-cell survival and lymphoid organogenesis. Participates also in the negative feedback of the non-canonical NF-kappa-B signaling pathway by phosphorylating and destabilizing MAP3K14/NIK. Within the nucleus, phosphorylates CREBBP and consequently increases both its transcriptional and histone acetyltransferase activities. Modulates chromatin accessibility at NF-kappa-B-responsive promoters by phosphorylating histones H3 at 'Ser-10' that are subsequently acetylated at 'Lys-14' by CREBBP. Additionally, phosphorylates the CREBBP-interacting protein NCOA3.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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