4-(Methylsulfonyl)benzyl+alcohol
Supplier:
BeanTown Chemical
Description:
CAS: 4931-66-2; EC No: 225-567-3; MDL No: MFCD00080931
Liquid; Molecular Formula: C6H9NO3; MW: 143.14
Boiling Point: 90°/0.3 mmHg; Flash point: <gt/>110°C (<gt/>230°F)
Density (g/mL): 1.226; Refractive Index: 1.486; Optical Rotation: [α]20/D +10.5°, c = 1 in ethanol
Catalog Number:
(103273-424)
Supplier:
Novus Biologicals
Description:
The DDX1 Antibody from Novus Biologicals is a rabbit polyclonal antibody to DDX1. This antibody reacts with human, mouse, rat. The DDX1 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(10262-366)
Supplier:
Bioss
Description:
Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin3, also known as DP103, DDX20, DEAD-box protein DP130 and DEAD/H box 20, is a protein product of human chromosome 1p13.2. It associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (for Gemini of the coiled bodies). Gemin3 also interacts with SmB, SmD2 and SmD3. It contains the conserved motif Asp-Glu-Ala-Asp (DEAD) characteristic of DEAD-box proteins. Gemin3 is a putative RNA helicase and shows ATPase activity. It is expressed in B and T cell neuroblastoma-derived cell lines, malignant melanoma tumor, normal testis and is expressed in low levels in colon, skeletal muscle, liver, kidney and lung.
Supplier:
Bachem Americas
Description:
This DSIP analog serves as a good substrate for protein L-isoaspartyl methyltransferase, a n enzyme occuring in the brain involved in the repair of age-damaged proteins containing atypical iosaspartyl peptide bonds.
Catalog Number:
(103269-906)
Supplier:
Novus Biologicals
Description:
The DDX47 Antibody from Novus Biologicals is a rabbit polyclonal antibody to DDX47. This antibody reacts with human, mouse, rat. The DDX47 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(10277-676)
Supplier:
Bioss
Description:
DDX3X is encoded by a gene found on the X chromosome while DDX3Y is encoded by a gene on the Y chromosome. DDX3Y is exclusively expressed in testis and is required for normal spermatogenesis. DDX3X is ubiquitously expressed and predominantly localizes to the nuclear speckles, participating in RNA splicing, transcription, translation initiation, mRNA transport and cell cycle regulation. DDX3X also partakes in HIV-1 replication and hepatitis C viral infections.
Catalog Number:
(G-1705.0001BA)
Supplier:
Bachem Americas
Description:
Also known as dioxopiperazines, piperazine-2,5-diones or DKPs. Diketopiperazines may occur as by-products during peptide synthesis or during the degradation of peptides. These cyclic dipeptides have been detected as taste-modulating compounds in food, they often show biological activity. DKPs are valuable chiral synthons, employed e.g. in Schöllkopf's versatile bislactim ether approach. They also have found use as catalysts for enantioselective synthesis, e.g. in the asymmetric Strecker reaction. See also the TRH metabolite cyclo(-His-Pro), G-1745, and cyclo(-Asp-Phe), G-1695, the major degradation product of aspartame.
Catalog Number:
(103636-698)
Supplier:
Sino Biological
Description:
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD46 (rh CD46; Catalog#12239-H08H; EAW93471.1; Met 1-Asp 328). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Catalog Number:
(103633-800)
Supplier:
Sino Biological
Description:
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PRMT6 (rh PRMT6; Catalog#11313-H18H; NP_060607.2; Met 1-Asp 375). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Catalog Number:
(103647-680)
Supplier:
Sino Biological
Description:
Produced in rabbits immunized with purified, recombinant Human Leukotriene A4 Hydrolase / LTA4H (rh Leukotriene A4 Hydrolase / LTA4H; Catalog#10276-H08B; NP_000886.1; Met 1-Asp 611). Leukotriene A4 Hydrolase / LTA4H specific IgG was purified by Human Leukotriene A4 Hydrolase / LTA4H affinity chromatography.
Catalog Number:
(10230-724)
Supplier:
Bioss
Description:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Catalog Number:
(TCM1861-5G)
Supplier:
TCI America
Description:
CAS Number: 6384-08-3
MDL Number: MFCD00171677 Molecular Formula: C6H11NO4 Molecular Weight: 161.16 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 145 Specific rotation [a]20/D: 35 deg (C=2, H2O)
Catalog Number:
(10233-058)
Supplier:
Bioss
Description:
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Catalog Number:
(10262-362)
Supplier:
Bioss
Description:
Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin3, also known as DP103, DDX20, DEAD-box protein DP130 and DEAD/H box 20, is a protein product of human chromosome 1p13.2. It associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (for Gemini of the coiled bodies). Gemin3 also interacts with SmB, SmD2 and SmD3. It contains the conserved motif Asp-Glu-Ala-Asp (DEAD) characteristic of DEAD-box proteins. Gemin3 is a putative RNA helicase and shows ATPase activity. It is expressed in B and T cell neuroblastoma-derived cell lines, malignant melanoma tumor, normal testis and is expressed in low levels in colon, skeletal muscle, liver, kidney and lung.
Supplier:
VWR
Description:
Reagent for stabilization of buffer formulations and electrophoresis of biological molecules.
Catalog Number:
(H-4772.0001BA)
Supplier:
Bachem Americas
Description:
This small molecule RGD peptidomimetic αvβ3 integrin antagonist contains both anionic and cationic binding sites that straddle the RGD binding domain of the αvβ3 integrin. The IC₅₀ for XJ 735 αvβ3-mediated inhibition of human and porcine cell adhesion, and vascular smooth muscle cell migration, ranged from 0.6 to 4.4 µM. In contrast, IC₅₀ for porcine or human αIIb/β3, α4β1, αvβ5, and α5β1 inhibition exceeded 100 µM.
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