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4-Azidobenzoic+acid
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4-Azidobenzoic+acid
Catalog Number:
(10401-354)
Supplier:
Bioss
Description:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
Catalog Number:
(RL008-0050)
Supplier:
Rockland Immunochemical
Description:
10mg. Antibody/Agarose: 1.5mg antigen per cc agarose. Agarose/Suspension: 0.5cc agarose per mL of suspension. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: None. For research.
Catalog Number:
(10433-586)
Supplier:
Bioss
Description:
This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1.
Catalog Number:
(10432-208)
Supplier:
Bioss
Description:
RAB proteins are GTPases that regulate vesicular trafficking and reside in specific intracellular compartments. RAB9 has been localized to components of the endocytic/exocytic pathway. It has been implicated in the recycling of membrane receptors, such as the mannose 6-phosphate receptor from early endosomes to the trans Golgi network.
Catalog Number:
(10433-588)
Supplier:
Bioss
Description:
This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1.
Catalog Number:
(10358-152)
Supplier:
Bioss
Description:
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
Catalog Number:
(10433-710)
Supplier:
Bioss
Description:
The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene.
Catalog Number:
(RL612-6102)
Supplier:
Rockland Immunochemical
Description:
Secondary Sheep Anti-IgG (H&L) Reacts with Rat
Catalog Number:
(RL009-0934)
Supplier:
Rockland Immunochemical
Description:
1mg. Antibody Concentration: 1 mg/mL. Fluorochrome/Protein: 3.4 moles Texas Red per mole of Human Transferrin. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: 10 mg/mL BSA IgG and protease free. For research. Lyophilized.
Catalog Number:
(RL012-0050)
Supplier:
Rockland Immunochemical
Description:
10mg. Antibody/Agarose: 2mg antibody per cc agarose. Agarose/Suspension: 0.5cc agarose per mL of suspension. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: None.
Catalog Number:
(10296-474)
Supplier:
Bioss
Description:
Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1.
Catalog Number:
(10359-980)
Supplier:
Bioss
Description:
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity (By similarity).
Catalog Number:
(10104-258)
Supplier:
Prosci
Description:
POLL is a repair polymerase.It is involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Catalog Number:
(76117-256)
Supplier:
Bioss
Description:
Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Involved in the activation of AKT1 upon stimulation by G-protein coupled receptors (GPCRs) ligands such as CXCL12, sphingosine 1-phosphate, and lysophosphatidic acid. May also act downstream receptor tyrosine kinases. Required in different signaling pathways for stable platelet adhesion and aggregation. Plays a role in platelet activation signaling triggered by GPCRs, alpha-IIb/beta-3 integrins (ITGA2B/ ITGB3) and ITAM (immunoreceptor tyrosine-based activation motif)-bearing receptors such as GP6. Regulates the strength of adhesion of ITGA2B/ ITGB3 activated receptors necessary for the cellular transmission of contractile forces. Required for platelet aggregation induced by F2 (thrombin) and thromboxane A2 (TXA2). Has a role in cell survival. May have a role in cell migration. Involved in the early stage of autophagosome formation. Modulates the intracellular level of PtdIns3P (Phosphatidylinositol 3-phosphate) and activates PIK3C3 kinase activity. May act as a scaffold, independently of its lipid kinase activity to positively regulate autophagy. May have a role in insulin signaling as scaffolding protein in which the lipid kinase activity is not required. May have a kinase-independent function in regulating cell proliferation and in clathrin-mediated endocytosis. Mediator of oncogenic signal in cell lines lacking PTEN. The lipid kinase activity is necessary for its role in oncogenic transformation. Required for the growth of ERBB2 and RAS driven tumors.
Catalog Number:
(102995-866)
Supplier:
Cell Sciences
Description:
IL-24, Monoclonal Antibody, Azide Free, Host: Mouse, Clone: B-C54, Isotype: IgG2a k, Species Reactivity: Human, Purification: Ion exchange chromatography, Formulation: Phosphate-buffered saline, Application: ELISA, Storage: +2-8deg C, Size: 500ug
Supplier:
Bachem Americas
Description:
Sequence: 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
Synonym(s): DPPE#L-β,γ-Dipalmitoyl-α-cephalin
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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