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Landiolol+hydrochloride
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Landiolol+hydrochloride
Catalog Number:
(10663-774)
Supplier:
Bioss
Description:
NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
Catalog Number:
(10663-768)
Supplier:
Bioss
Description:
NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
Catalog Number:
(10663-776)
Supplier:
Bioss
Description:
NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Xylenol orange tetrasodium salt, water soluble, pure
Catalog Number:
(77437-560)
Supplier:
Bioss
Description:
Serine/threonine-protein kinase involved in variousprocesses such as cell cycle regulation, gluconeogenesis andlipogenesis regulation, muscle growth and differentiation and tumorsuppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1,TORC1/CRTC1 and TORC2/CRTC2. Acts as a tumor suppressor and plays akey role in p53/TP53-dependent anoikis, a type of apoptosistriggered by cell detachment: required for phosphorylation ofp53/TP53 in response to loss of adhesion and is able to suppressmetastasis. Part of a sodium-sensing signaling network, probably bymediating phosphorylation of PPME1: following increases inintracellular sodium, SIK1 is activated by CaMK1 and phosphorylatesPPME1 subunit of protein phosphatase 2A (PP2A), leading todephosphorylation of sodium/potassium-transporting ATPase ATP1A1and subsequent increase activity of ATP1A1. Acts as a regulator ofmuscle cells by phosphorylating and inhibiting class II histonedeacetylases HDAC4 and HDAC5, leading to promote expression of MEF2target genes in myocytes. Also required during cardiomyogenesis byregulating the exit of cardiomyoblasts from the cell cycle viadown-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepaticgluconeogenesis by phosphorylating and repressing the CREB-specificcoactivators TORC1/CRTC1 and TORC2/CRTC2, leading to inhibit CREBactivity. Also regulates hepatic lipogenesis by phosphorylating andinhibiting SREBF1.
Catalog Number:
(77981-762)
Supplier:
LGC STANDARDS
Description:
(3’S,3R,4S)-Desfluoro Ezetimibe, TRC, LGC Standards
Catalog Number:
(77982-177)
Supplier:
LGC STANDARDS
Description:
3,3'-Diaminobenzidine, TRC, LGC Standards
Catalog Number:
(100504-242)
Supplier:
Electron Microscopy Sciences
Description:
Ultrastructural localization sodium. Reference: J. Histochem Cystochem., 24, 740 (1976).
Supplier:
TCI America
Description:
CAS Number: 3599-32-4
MDL Number: MFCD00013078 Molecular Formula: C43H48N2O6S2 Molecular Weight: 774.97 Form: Crystal Color: Yellow
Supplier:
Thermo Scientific Chemicals
Description:
A fluorophore comonly used in microscopy
Catalog Number:
(10206-050)
Supplier:
Boster Biological Technology
Description:
Rabbit IgG polyclonal antibody for Sodium-dependent serotonin transporter(SLC6A4) detection. Tested with WB in Human.
Catalog Number:
(TCI0007-025G)
Supplier:
TCI America
Description:
CAS Number: 928-72-3
MDL Number: MFCD00043340 Molecular Formula: C4H7NO4 Molecular Weight: 177.07 Purity/Analysis Method: >98.0% (T) Form: Crystal
Catalog Number:
(77982-662)
Supplier:
LGC STANDARDS
Description:
Digoxigenin Bisdigitoxoside, TRC, LGC Standards
Catalog Number:
(77982-569)
Supplier:
LGC STANDARDS
Description:
Diethyl Carbonate, TRC, LGC Standards
Catalog Number:
(77977-333)
Supplier:
LGC STANDARDS
Description:
N-(2-Aminophenyl)-N’-phenylheptanediamide, TRC, LGC Standards
Catalog Number:
(77982-038)
Supplier:
LGC STANDARDS
Description:
Desoxycarbadox-D3, TRC, LGC Standards
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is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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