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(Bromomethyl)cyclobutane
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(Bromomethyl)cyclobutane
Supplier:
AMBEED, INC
Description:
4-(Bromomethyl)-1-fluoro-2-nitrobenzene 98%
Supplier:
Matrix Scientific
Description:
MF=C7H5Br2Cl MW=284.39 Cas=68120-44-5 MDL=MFCD08059101 5G
Catalog Number:
(77410-148)
Supplier:
APOLLO SCIENTIFIC
Description:
2-(Bromomethyl)-5-nitropyridine > 97%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
(Bromomethyl)triphenylphosphonium bromide 98%
Supplier:
AMBEED, INC
Description:
4'-(Bromomethyl)-2-fluoro-1,1'-biphenyl, Purity: 97%, CAS Number: 193013-76-2, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 1g
Catalog Number:
(10319-736)
Supplier:
Bioss
Description:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilize XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Supplier:
Matrix Scientific
Description:
2-Bromomethyl-1,4-benzodioxane ≥97%
Supplier:
AMBEED, INC
Description:
4-(Bromomethyl)tetrahydropyran, Purity: 95%, CAS Number: 125552-89-8, Appearance: Colorless to yellow to brown liquid, Storage: Inert atmosphere, 2-8 C, Size: 5g
Supplier:
Thermo Scientific Chemicals
Description:
Applications: Fluorescent labeling reagent. used in HPLC for the detection of carboxylic acids
Catalog Number:
(76688-250)
Supplier:
AMBEED, INC
Description:
3-(Bromomethyl)-5-chlorobenzo[b]thiophene 98%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 054206-500MG , MDL Number: MFCD12025360
Supplier:
AMBEED, INC
Description:
Methyl 2-(bromomethyl)-5-cyanobenzoate 95%
Catalog Number:
(101921-014)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 060956-500MG , MDL Number: MFCD19103420
Supplier:
Matrix Scientific
Description:
MF=C9H11BR MW=199.10 CAS=83902-02-7 MDL=MFCD03844742 5G
Catalog Number:
(76647-310)
Supplier:
AMBEED, INC
Description:
5-(Bromomethyl)-2-fluoropyridine hydrobromide, Purity: 95%, CAS Number: 31140-61-1, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 250MG
Supplier:
AMBEED, INC
Description:
3-(Bromomethyl)oxetane 95%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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