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(Bromomethyl)cyclobutane
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(Bromomethyl)cyclobutane
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 058781-1G , MDL Number: MFCD02677720
Catalog Number:
(101920-350)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 060619-500MG , MDL Number: MFCD00101673
Catalog Number:
(TCB2158-5G)
Supplier:
TCI America
Description:
CAS Number: 35168-64-0
MDL Number: MFCD01114746 Molecular Formula: C12H16Br2 Molecular Weight: 320.07 Purity/Analysis Method: >98.0% (GC) Form: Crystal
Catalog Number:
(77686-465)
Supplier:
AMBEED, INC
Description:
2-(Bromomethyl)-4-(trifluoromethoxy)phenylboronic acid pinacol ester ≥98%
Catalog Number:
(102842-110)
Supplier:
Matrix Scientific
Description:
2-[3-(Bromomethyl)-5-(1-cyano-1-methylethyl)phenyl]-2-methylpropanenitrile ≥97%
Catalog Number:
(TCB0847-025G)
Supplier:
TCI America
Description:
CAS Number: 16532-02-8
MDL Number: MFCD00000503 Molecular Formula: C3H8BrClSi Molecular Weight: 187.54 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 135 Flash Point (°C): 41 Specific Gravity (20/20): 1.39
Supplier:
AMBEED, INC
Description:
4-Bromo-3-(bromomethyl)benzonitrile, Purity: 95%, CAS Number: 190197-86-5, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 1g
Supplier:
AMBEED, INC
Description:
2-(5-(Bromomethyl)-2-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, Purity: 95%, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 250MG
Supplier:
TCI America
Description:
CAS Number: 22262-60-8
MDL Number: MFCD00011534 Molecular Formula: C5H8Br2O2 Molecular Weight: 259.93 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 62 Flash Point (°C): 113 Specific Gravity (20/20): 1.85
Supplier:
Matrix Scientific
Description:
MF=C6H5BRCLN MW=206.48 CAS=182924-36-3 MDL=MFCD07368893 1G
Supplier:
AMBEED, INC
Description:
1-Bromo-2-(bromomethyl)naphthalene, Purity: 98%, CAS Number: 37763-43-2, Appearance: Form: powder, Storage: Inert atmosphere, Room Temperature, Size: 25G
Catalog Number:
(76677-594)
Supplier:
AMBEED, INC
Description:
3-(Bromomethyl)-2-chloro-6-fluoropyridine, Purity: 97%, CAS Number: 1227516-84-8, Appearance: Solid or semi-solid or lump or liquid, Storage: Inert atmosphere, Store in freezer, under -20C, Size: 250MG
Catalog Number:
(10451-498)
Supplier:
Bioss
Description:
Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Supplier:
TCI America
Description:
CAS Number: 41459-42-1
MDL Number: MFCD00010643 Molecular Formula: C4H6Br2O2 Molecular Weight: 245.90 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 99 Storage Temperature: 0-10°C
Supplier:
TCI America
Description:
CAS Number: 58539-11-0
MDL Number: MFCD00034154 Molecular Formula: C6H10Br2O2 Molecular Weight: 273.95 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 86 Flash Point (°C): 113 Specific Gravity (20/20): 1.72
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