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2,2'-Dithiodi(benzoic+acid)
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2,2'-Dithiodi(benzoic+acid)
Catalog Number:
(10353-020)
Supplier:
Bioss
Description:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Catalog Number:
(10413-230)
Supplier:
Bioss
Description:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Catalog Number:
(80109-738)
Supplier:
MilliporeSigma
Description:
A boronic acid-based, reversible proteasome inhibitor that is structurally similar to MG-132 (80053-194, -196) but displays much higher potency (Ki=0.03nM vs)
Catalog Number:
(BT136680-5G)
Supplier:
BeanTown Chemical
Description:
CAS: 82121-05-9; MDL No: MFCD00169015
UN No: UN3335; Haz Class: 9; Packing Group: III
Powder; Molecular Formula: C9H8N2O2; MW: 175.18
Melting Point: 213-217°
Supplier:
Biolegend
Description:
CD5 Monoclonal Antibody, Clone: 53-7.3, Host: Rat, Species reactivity: Mouse, Isotype: IgG2a, K, Conjugate: PE/Dazzle 594, Immunogen: Mouse thymus, Formulation: Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, Synonyms: Lyt-1, Ly-1, Storage: between 2 deg C and 8 deg C, Size: 100ug
Supplier:
Biolegend
Description:
CD4 Monoclonal Antibody, Clone: GK1.5, Host: Rat, Species reactivity: Mouse, Isotype: Rat IgG2b, K, Conjugate: Spark NIR 685, Immunogen: CTL clone V4, Formulation: Phosphate-buffered solution, pH 7.2, Synonyms: L3T4, T4, Storage: between 2 deg C and 8 deg C, Application: FC, Size: 25ug
Catalog Number:
(76422-444)
Supplier:
Biolegend
Description:
CD154, Recombinant Monoclonal Antibody, Clone: QA17A53, Host: Rat, Species Reactivity: Mouse, Isotype: IgG1, K, Conjugate: PE, Other Names: CD40 ligand (CD40L), gp39, T-BAM, TRAP, Ly-62, TNFSF5, Formulation: Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, Size: 25 uG
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Guanosine-5'-monophosphate disodium salt 97%
Catalog Number:
(76422-760)
Supplier:
Biolegend
Description:
CD8a Monoclonal Antibody, Clone: 53-6.7, Host: Rat, Species: Mouse, Isotype: IgG2a, K, Conjugate: TotalSeq C0002, Immunogen: Mouse thymus, Formulation: Phosphate-buffered soln, pH 7.2, 0.09% sodium azide, Synonyms: T8, Lyt2, Storage: between 2 deg C and 8 deg C, Application: FC, Size: 10 ug
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to an 85 kDa protein known as XRCC1. X-ray repair cross complementing 1 (XRCC1) protein plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels.
Catalog Number:
(76422-694)
Supplier:
Biolegend
Description:
CD51 Monoclonal Antibody, Clone: RMV-7, Host: Rat, Species reactivity: Mouse, Isotype: IgG1, K, Conjugate: TotalSeq A1008, Immunogen: BALB/c ms IL2-activated cells, Formulation: Phosphate solution, pH 7.2, 0.09% sodium azide, Synonyms: Integrin AV chain, ITGAV, Application: FC, Size: 10ug
Catalog Number:
(10254-418)
Supplier:
Bioss
Description:
The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Synaptojanins are characterized by an N-terminal SAC1-like sequence, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4,5-bisphosphate as a substrate. Synaptojanins exist as two isoforms, synaptojanin 1 and 2, which differ in the C-terminal domain, and each isoform has multiple variants produced by alternative splicing. Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues. Eight splice variants of synaptojanin 2 have been detected, including a brain specific isoform. Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton.
Catalog Number:
(10299-294)
Supplier:
Bioss
Description:
GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
Catalog Number:
(10360-038)
Supplier:
Bioss
Description:
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity (By similarity).
Catalog Number:
(10360-034)
Supplier:
Bioss
Description:
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity (By similarity).
Catalog Number:
(76011-690)
Supplier:
Prosci
Description:
NUDT9 hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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