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Methyl heptadecanoate

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Description:   Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters. [SUBUNIT] Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus. Belongs to the SREBP family.
Catalog Number: 10306-000
Supplier: Bioss



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Description:   MDL: MFCD00064844
Catalog Number: AA11122-18
Supplier: Thermo Scientific Chemicals



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Description:   MDL: MFCD00150232
Catalog Number: AA40576-NE
Supplier: Thermo Scientific Chemicals



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Description:   Catalyst, corrosion inhibitor, in textile printing
Catalog Number: AA11565-30
Supplier: Thermo Scientific Chemicals



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MSDS SDS Certificate Certificates    
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Description:   MDL: MFCD00149870
Catalog Number: AA44472-14
Supplier: Thermo Scientific Chemicals



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Description:   CAS: 12032-20-1; EC No: 234-764-3; MDL No: MFCD00011100 Powder; Molecular Formula: Lu2O3; MW: 397.94 Density (g/mL): 9.42 Hygroscopic
Catalog Number: BT129195-5G
Supplier: BeanTown Chemical



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Description:   Rhodium(III) chloride hydrate 99.95% (trace metals basis)
Catalog Number: TS43709-2500
Supplier: THERMO FISHER SCIENTIFIC CHEMICALS



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Description:   Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
Catalog Number: 10389-494
Supplier: Bioss



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Description:   MDL: MFCD00010949
Catalog Number: AA10688-36
Supplier: Thermo Scientific Chemicals



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Description:   CAS #: 18039-90-2. Size: 5g.
Catalog Number: 100208-382
Supplier: Strem Chemicals Inc



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Description:   CAS #: 1303-58-8. Size: 1g.
Catalog Number: 100202-728
Supplier: Strem Chemicals Inc



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Description:   CAS #: 12030-24-9. Size: 25g.
Catalog Number: 100198-398
Supplier: Strem Chemicals Inc



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Description:   Phosphorus(III) bromide 1 mol/l in dichloromethane, AcroSeal®
Catalog Number: TS382061000
Supplier: THERMO FISHER SCIENTIFIC CHEMICALS


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Description:   UBC13 Antibody: Ubiquitin-conjugating enzyme 13 (Ubc13) was initially discovered in S. cerevisiae as a DNA-damage inducible protein involved in the error-free DNA postreplication repair pathway. It has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway. Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors. Ubc13 is part of a dimeric ubiquitin-conjugating enzyme complex also containing UEV1A (ubiquitin-conjugating enzyme E2 variant 1) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kinase kinase kinase family. The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6, and this ubiquitination is essential for TAK1 activation.
Catalog Number: 89415-720
Supplier: Prosci



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Description:   Iron(III) phosphate hydrate, extra pure
Catalog Number: TS38995-5000
Supplier: THERMO FISHER SCIENTIFIC CHEMICALS



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Description:   Alkoxide
Catalog Number: 100206-778
Supplier: Strem Chemicals Inc



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