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Cyclopropyl(2,3-difluoro-4-pyridinyl)methanone
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Cyclopropyl(2,3-difluoro-4-pyridinyl)methanone
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 035595-5G , MDL Number: MFCD02093072
Catalog Number:
(102550-830)
Supplier:
Matrix Scientific
Description:
METHYL 6-FLUOROSALICYLATE MF=C8H7FO3 MW=170.14 CAS=72373-81-0 MDL=MFCD00153207
Supplier:
AMBEED, INC
Description:
LY-2835219 ≥98%, Ambeed.Inc
Catalog Number:
(101801-468)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 011864-500MG , MDL Number: MFCD02741579
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 047305-500MG , MDL Number: MFCD09027102
Supplier:
AMBEED, INC
Description:
Methyl-3-fluoropicolinate 98%
Supplier:
AMBEED, INC
Description:
4-Fluorothioanisole 98%
Catalog Number:
(101836-802)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 034010-500MG , MDL Number: MFCD04971027
Supplier:
AMBEED, INC
Description:
(R)-6-(1-(8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one, Purity: 98+%, CAS Number: 1173699-31-4, Appearance: Solid, Storage: Sealed in dry, 2-8 C, Size: 10mg
Catalog Number:
(101909-720)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 055582-100MG , MDL Number: MFCD15530281
Supplier:
Matrix Scientific
Description:
MF=C8H7Fo2 MW=154.14 Cas=33184-16-6 MDL=MFCD00042294 5G
Supplier:
Adipogen
Description:
Inhibitor of pan-Trk activity (IC(50) = 8 and 12nM for TrkA and TrkB). Shown to target Trk (tropomyosin receptor kinase) ATP binding cleft and an immediately adjacent hydrophobic pocket. Preferentially arrests the proliferation of Ba/F3 cells fused with Tel-TrkA, Tel-TrkB and Tel-TrkC (IC(50) = 11, 9 and 7nM, respectively) and in Ba/F3 and RIE cells expressing both TrkA and NGF (IC(50) = 42 and 17nM, respectively) over Mo7e-c-Kit and Rat-A10-PDGFR (IC(50) = 1 and 0.5µM) and Ba/F3-Tel-KDR and wt-Ba/F3 cells (IC(50) = 3.0 and 5.6µM). Displays ~100-fold greater selectivity among a panel of 59 closely related kinases and in 33 cellular kinase assays. Weakly active against relevant cytochrome P450 isozymes and hERG channel, and exhibit adequate microsomal stability, pharmacokinetic profile and efficacy in mice and rats. Suppresses tumor growth in a mouse RIE-TrkAmNGF xenograft model (50mg/kg, p.o.).
Supplier:
Thermo Scientific Chemicals
Description:
5g CAS: 405-66-3, MDL: MFCD03839848
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 045112-5G , MDL Number: MFCD05663793
Supplier:
Matrix Scientific
Description:
2'-Methyl-2,2,2,4'-tetrafluoroacetophenone ≥97%
Supplier:
AMBEED, INC
Description:
4-Fluoro-3-methylbenzoic acid, Purity: 97%, CAS number: 403-15-6, Appearance: Form: Crystal - Powder, Storage: Sealed in dry, Room Temperature, Size: 5G
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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