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Diphenyl Phenylphosphonate
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Diphenyl Phenylphosphonate
Catalog Number:
(100271-384)
Supplier:
Indofine Chemical Company
Description:
Rare Organics & BioChemicals 3397-32-8 5gm Z-Phe-OSu 396.4 Room temperature.
Supplier:
AMBEED, INC
Description:
Z-D-Dab(Boc)-OH·DCHA 97%
Catalog Number:
(77686-103)
Supplier:
AMBEED, INC
Description:
Boc-D-Dap(Z)-OH·DCHA ≥95%
Supplier:
Bachem Americas
Description:
Sequence: Z-Tyr-OBzl
Supplier:
AMBEED, INC
Description:
O-tert-Butyl-N-carbobenzoxy-L-serine methyl ester 95%
Supplier:
AMBEED, INC
Description:
N-Carbobenzoxy-L-serine benzyl ester 98%
Supplier:
ALADDIN SCIENTIFIC
Description:
Product DescriptionDGAT-1 inhibitor A 922500 (A-922500) reduces serum triglyceride levels from baseline at all doses tested; however, this is only statistically significant at the 3 mg/kg dose, which lowers serum triglycerides by 53%. Similarly, the 3 mg/kg dose of A 922500 significantly reduces serum FFA concentrations by 55% and total cholesterol by 25%. DGAT-1 inhibition has no significant effect on body weight at any dose tested. Although A 922500 dpes not significantly affect LDL-cholesterol or HDL-cholesterol individually, the serum LDL/HDL-cholesterol ratio is significantly improved by A 922500 at 0.3 and 3 mg/kg. Similar to the dyslipidemic hamster, treatment with 3 mg/kg A 922500 significantly reduces serum triglyceride concentrations (39%). FFA levels significantly increase over the 14-day period in vehicle-treated animals. This increase is inhibited in a dose-dependent manner by A 922500 such that FFA concentrations are 32% lower after 14 days of treatment with the DGAT-1 inhibitor at 3 mg/kg, compared with the vehicle group (p < 0.05). HDL-cholesterol is significantly increased from baseline levels by A 922500 at 0.3 and 3 mg/kg; however, this is only significantly increased compared with vehicle at the 3 mg/kg dose. Body weight significantly increases over the 2-week period in vehicle-treated rats, and this is not affected by A 922500. LDL-cholesterol is significantly reduced in the vehicle treated group. DGAT-1 inhibition does not further reduce LDL-cholesterol and has no effect on total cholesterol.Product ApplicationA922500 has been used in the inhibition of diacylglycerol acyltransferase (DGAT) in epithelial human breast cancer cell line (MDA-MB-231), digitonin-permeabilized human cancer cells, human myotubes and macrophages.
Catalog Number:
(101917-188)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059124-1G , MDL Number: MFCD00136653
Supplier:
AMBEED, INC
Description:
Potassium (4-(cbz-amino)phenyl)trifluoroborate 98%
Catalog Number:
(76998-342)
Supplier:
AMBEED, INC
Description:
Dicyclohexylamine (2S,3R)-2-(((benzyloxy)carbonyl)amino)-3-(tert-butoxy)butanoate, Purity: 97%, CAS number: 16966-07-7, Appearance: White to off-white powder or crystals, Storage: Inert atmosphere, 2-8C, Size: 100G
Catalog Number:
(102541-576)
Supplier:
Matrix Scientific
Description:
MF=C20H18N4O4 MW=378.39 CAS=152120-55-3 MDL=MFCD02092983 5G
Supplier:
AMBEED, INC
Description:
PHA-665752 99%
Supplier:
Bachem Americas
Description:
Sequence: Z-Ala-OSu
Supplier:
Bachem Americas
Description:
Sequence: H-Lys(Z)-OtBu · HCl
Supplier:
BeanTown Chemical
Description:
CAS: 88568-95-0; MDL No: MFCD00043304
Powder; Molecular Formula: C13H18NO7P; MW: 331.26
Melting Point: 76-80°
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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