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2-(Isopropylamino)-5-pyrimidineboronic+acid+pinacol+ester
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2-(Isopropylamino)-5-pyrimidineboronic+acid+pinacol+ester
Supplier:
AMBEED, INC
Description:
4-(n-Butoxy)benzenesulfonyl chloride 98%
Supplier:
BeanTown Chemical
Description:
CAS: 7758-89-6; EC No: 231-842-9; MDL No: MFCD00010971; RTECS: GL6990000
UN No: UN2802; Haz Class: 8; Packing Group: III
Powder; Linear Formula: CuCl; MW: 98.99
Melting Point: 430°; Boiling Point: 1490°
Density (g/mL): 4.14
Air Sensitive, Moisture Sensitive
Supplier:
TCI America
Description:
CAS Number: 98-74-8
MDL Number: MFCD00007445 Molecular Formula: C6H4ClNO4S Molecular Weight: 221.61 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Boiling point (°C): 181 Melting point (°C): 79
Supplier:
BeanTown Chemical
Description:
CAS: 5810-42-4; EC No: 227-375-5; MDL No: MFCD00038729
Crystalline; Linear Formula: (CH3CH2CH2)4N(Cl); Molecular Formula: C12H28ClN; MW: 221.81
Melting Point: 240-242°
Hygroscopic
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Methyl malonyl chloride 97%
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00007247
Beilstein Registry No.: 777186
Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 68800-33-9, MDL: MFCD08706420
Supplier:
Thermo Scientific Chemicals
Description:
500ml CAS: 931-51-1, MDL: MFCD00003816
Supplier:
AMBEED, INC
Description:
(4-Nitrophenyl)methanesulfonyl chloride, Purity: 95%, CAS Number: 4025-75-6, Appearance: Solid, Storage: Inert atmosphere, 2-8 deg C, Size: 25g
Catalog Number:
(AAH34455-03)
Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 10130-87-7, MDL: MFCD01961367
Supplier:
TCI America
Description:
CAS Number: 112-02-7
MDL Number: MFCD00011773 Molecular Formula: C19H42ClN Molecular Weight: 320.00 Purity/Analysis Method: >95.0% (T) Form: Crystal Melting point (°C): 234
Catalog Number:
(76084-192)
Supplier:
Bioss
Description:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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