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2-(4-Bromo-2-methylphenyl)acetonitrile
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2-(4-Bromo-2-methylphenyl)acetonitrile
Catalog Number:
(IC10250290)
Supplier:
MP Biomedicals
Description:
Olive oil is commonly used in cooking, cosmetics, pharmaceuticals, and soaps and as a fuel for traditional oil lamps.
Catalog Number:
(102990-314)
Supplier:
Adipogen
Description:
Fluorogenic substrate for leucine aminopeptidase. Sensitivity of fluorescence detection is greatly increased over other methods such as 4-Methoxy-naphthylamide (pNA) assays.
Catalog Number:
(TCV0050-025ML)
Supplier:
TCI America
Description:
CAS Number: 34937-00-3
MDL Number: MFCD00060149 Molecular Formula: C17H30N2O3Si Molecular Weight: 374.98 Form: Clear Liquid Color: Yellow Flash Point (°C): 12
Catalog Number:
(10426-346)
Supplier:
Bioss
Description:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
Catalog Number:
(TCT2593-1G)
Supplier:
TCI America
Description:
CAS Number: 175278-07-6
MDL Number: MFCD00153285 Molecular Formula: C8H7F3O2 Molecular Weight: 192.14 Purity/Analysis Method: >96.0% (GC) Form: Clear Liquid Color: Very Pale Yellow Boiling point (°C): 98 Specific Gravity (20/20): 1.33
Supplier:
BeanTown Chemical
Description:
CAS: 98-55-5; EC No: 202-680-6; MDL No: MFCD00001557; RTECS: WZ6700000
Liquid ; Molecular Formula: C10H18O; MW: 154.24
Melting Point: 31-35°; Boiling Point: 217-218°; Flash point: 90°C (194°F)
Density (g/mL): 0.93; Refractive Index: 1.482
Supplier:
MP Biomedicals
Description:
Thymidine is a nucleoside composed of deoxyribose (a pentose sugar) joined to the pyrimidine base thymine.Deoxythymidine can be phosphorylated with one, two or three phosphoric acid groups, creating respectively dTMP, dTDP or dTTP (deoxythymidine mono- di- or triphosphate.It exists in solid form as small white crystals or white crystalline powder.The stability of deoxythymidine under standard temperature and pressure (STP) is very high.Thymidine is listed as a chemical teratogen.
Mainly used in forming hybrid cell lines wherein cells are incubated in HAT medium(hypoxanthine-aminopterin-thymidine medium) to give rise to monoclonal antibodies. Use in HT and HAT cocktails for hybridoma fusion, selection and cloning. Physical Appearance: White Powder Optical Rotation: (c=1, water) +17.5 - +19.5° UV/Visible Absorbance: λmax (0.1N HCl) 266 - 268 nm Solubility: Soluble in water, methanol, hot alcohol, hot acetone, hot ethyl acetate pyridine, glacial acetic acid and HCl (20 mg/mL-clear, colorless solution); sparingly soluble in hot chloroform
Catalog Number:
(102988-950)
Supplier:
Adipogen
Description:
Resorcylic acid lactone. Mycotoxin. Regulator of fungal morphogenesis. Mycoestrogen with anabolic and uterotrophic activity. Ecdysteroid antagonist. Gonadotropin inhibitor. Interleukin antagonist. Apoptosis inducer. Analytical standard in food industry.
Supplier:
Adipogen
Description:
Redox indicator. Blue fluorescence until oxidized to ethidium. Can be used for detecting superoxide radical in cells, tissues and organisms.
Supplier:
MP Biomedicals
Description:
Clomiphene Citrate Salt is a mixture of cis- and trans- isomers. Clomiphene citrate is a selective estrogen receptor modulator.
Catalog Number:
(10426-342)
Supplier:
Bioss
Description:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
Supplier:
Adipogen
Description:
N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasma membranes.
Supplier:
Adipogen
Description:
Antibiotic. Antiprotozoal. Antimicrobial. Cytotoxic and genotoxic in various mammalian cells. Mitochondrial permeability transition pore (MPTP) activator. Apoptosis inducer. ERK and JNK signaling pathways activator. Nephrotoxic mycotoxin. Suppresses NO and iNOS expression via inhibition of the JAK/STAT-1alpha and NF-kappaB signaling pathways. Tubulin polymerization and mitotic spindle assembly inhibitor. Increases reactive oxygen species (ROS). Induces cell cycle arrest at the G0/G1 and G2/M phase.
Supplier:
Biotium
Description:
One-Step Lumitein™ Protein Gel Stain is a ready-to-use luminescent red protein gel stain. It is a dramatically improved version of our original Lumitein™ protein gel stain in terms of convenience and safety. One-Step Lumitein™ can detect as little as approximately 1-10 ng of protein per band.
Supplier:
Restek
Description:
In support of the U.S. Safe Drinking Water Act (SDWA), Restek offers a complete set of EPA 524.3 reference standards for the monitoring of purgeable organic compounds in drinking water—using as few as three ampuls! In addition, this collection of certified reference materials (CRMs) also covers the seven volatile organic compounds (VOCs) included in the Unregulated Contaminant Monitoring Rule 3 (UCMR3), which requires monitoring of all public drinking water systems with 10,000 or more customers.
Catalog Number:
(76078-728)
Supplier:
Bioss
Description:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both <i>in vivo</i> and <i>in vitro</i>. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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