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[2-(Methylamino)-5-nitrophenyl]methanol
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[2-(Methylamino)-5-nitrophenyl]methanol
Supplier:
Thermo Scientific Chemicals
Description:
In manufacturing of HNO₃, as a catalyst to manufacture H₂SO₄, in manufacturing of glass, enamel for pottery, sodium nitrite
Supplier:
Thermo Scientific Chemicals
Description:
Pharmaceuticals, air-conditioning, humectant, drying agent, batteries, low temperature heat-exchange medium
Supplier:
MP Biomedicals
Description:
Erythrosin B is a red, anionic xanthene dye.
Supplier:
Adipogen
Description:
Cell permeable, non-alkylating, non-thiol, adduct-forming, redox cycling quinone. Intracellular superoxide anion formation/ROS generation inducer. Anticancer agent. Shown to induce cell proliferation, apoptosis, necrosis and necroptosis in vitro, dependent on concentration, time, temperature and cell type. Valuable tool for the generation of reactive oxygen species (ROS) in order to study the role of ROS in cell toxicity, apoptosis and necrosis. Useful as reference compound in characterizing the effects of oxidative stress. Can be used to eliminate any mechanistic ambiguity involving redox cycling quinoids as the source of reactive oxidant species/oxidative stress in biological studies.
Supplier:
Adipogen
Description:
Highly potent, selective and reversible cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome. Calpain and cathepsin inhibitor. Autophagy activator. Anticancer compound. Inhibits proliferation and migration of several tumor cell lines with nanomolar potency. Apoptosis inducer.
Catalog Number:
(102988-740)
Supplier:
Adipogen
Description:
Non-cytotoxic melanogenesis inhibitor. Potential depigmentation agent. Tyrosinase-related protein 2 (TRP-2) expression inhibitor, via proteasomal degradation. Inhibits the proliferation of melanocytes and melanoma cells through cell cycle arrest in G1. Moderate skin tumor growth suppressor in vivo.
Supplier:
Electron Microscopy Sciences
Description:
A ready-to-use stain for bone marrow staining.
Supplier:
Adipogen
Description:
Analgesic compound. Main active metabolite of tramadol. More potent as a µ: opioid agonist compared to tramadol. High-affinity ligand of the delta- and kappa-opioid receptors. Inactive as serotonin reuptake inhibitor. Compound can be used as analytical reference material.
Supplier:
Adipogen
Description:
Chirality inducing agent. Useful tool as resolving agent to separate the isomers and purify racemic mixtures (e.g. DL-lysine) by fractionally crystallizing the product to obtain the pure isomer (e.g. D-lysine). Can also be used as building block.
Catalog Number:
(76078-726)
Supplier:
Bioss
Description:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both <i>in vivo</i> and <i>in vitro</i>. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
Supplier:
Adipogen
Description:
2-heptyl-3-hydroxy-4-quinolone can function as an intercellular signal. Quorum sensing-regulated virulence factor used to induce and study the regulation of virulence genes such as those involved in iron scavenging. Quorum sensing is a signaling system used by bacteria to coordinate activity based upon their population density. The system involves the exchange of signaling molecules among bacteria via cell receptors.
Catalog Number:
(IC15255405)
Supplier:
MP Biomedicals
Description:
Phenol Red Sodium Salt is used as a pH indicator, it is used widely in culture media to identify changes from neutral to acidic pH values.
Supplier:
AMBEED, INC
Description:
4-Methoxybenzhydrol 98%
Supplier:
Adipogen
Description:
Keto acid that is involved in the tyrosine catabolism pathway. It is a product of the enzyme (R)-4-hydroxyphenyllactate dehydrogenase and is formed during tyrosine metabolism. The conversion from tyrosine to 4-HPPA is catalyzed by tyrosine aminotransferase. 4-HPPA can be converted to homogentisic acid which is one of the precursors to ochronotic pigment. A deficiency in the catalytic activity of HPD is known to lead to tyrosinemia type III, an autosomal recessive disorder characterized by elevated levels of blood tyrosine and massive excretion of tyrosine derivatives into urine.
Supplier:
MP Biomedicals
Description:
2-Methylisothiazolone (MIT) are chemical compounds used as highly effective biocidal agents against fungal and bacterial species. They are widely used as a preservative in cosmetic industry, and as a pesticide, e.g. in paints and water tanks.
Supplier:
MP Biomedicals
Description:
Dimethyl Pimelimidate Dihydrochloride is a bifunctional cross linking reagent used in peptide research.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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