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3-[(3-Fluorophenyl)amino]propanoic+acid
Supplier:
Adipogen
Description:
Polo-like kinase 1 (Plk1) is a regulator of the cell cycle that has been implicated in the pathology of many cancers. BI-2536 is a potent and selective small-molecule inhibitor of mammalian Plk1. It has inhibitory activity at subnanomolar concentrations and inhibits tumor growth in multiple tumor lines with IC(50) values below 1µM. BI-2536 also shows an >1,000-fold selectivity for PIK1 versus a large panel of other kinases. BI-2536 also demonstrated low Kd values against sister kinases PLK2 and PLK3. Preclinical studies in human cancer cell lines have shown that BI 2536 disrupts spindle assembly, resulting in mitotic arrest and inducing apoptosis. BI-2536 is currently in clinical trials against several types of solid tumor cancers.
Supplier:
TCI America
Description:
[Optical Resolving]
CAS Number: 20445-31-2 MDL Number: MFCD00004184 Molecular Formula: C10H9F3O3 Molecular Weight: 234.17 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Flash Point (°C): 112 Freezing point (°C): 35 Specific rotation [a]20/D: 72 deg (C=2, MeOH)
Supplier:
VWR
Description:
Non ionic detergent efficiently separate hydrophilic proteins from membrane spanning, hydrophobic proteins without altering biological activity.
Supplier:
AOB CHEM USA
Description:
5-Bromo-3-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid ≥97%
Supplier:
Thermo Scientific Chemicals
Description:
Phenyl 4-(trifluoromethyl)phenyl carbinol 4-(Trifluoromethyl)diphenylmethanol. Grade: 97. Melting Point C59-61*. Boiling Point C: 122-124*/0. 4mm. C14H11F3O. 395-23-3. IRRITANT
Supplier:
Adipogen
Description:
BI-D1870 is a small molecule, specific inhibitor of p90 RSK (ribosomal S6 kinase) isoforms RSK1, RSK2, RSK3 and RSK4, both in vitro and in vivo, with IC(50)s are 31nM, 24nM, 18nM, 15nM, respectively. It shows a 10- to 100-fold selectivity for RSK over MST2, GSK-3beta, MARK3, CK1 and Aurora B.
Supplier:
AOB CHEM USA
Description:
(4-Fluoro-[1,1'-biphenyl]-3,5-diyl)bis(methylsulfane) ≥97%
Supplier:
AMBEED, INC
Description:
(1-Hydroxyethylidene)bis-phosphonic acid tetrasodium salt, Purity: 98%, CAS Number: 3794-83-0, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 100g
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 045728-1G , MDL Number: MFCD05663813
Supplier:
Matrix Scientific
Description:
MF=C9H6F4O2 MW=222.14 Cas=220227-66-7 MDL=MFCD00061187 ,5G
Supplier:
TCI America
Description:
CAS Number: 51-36-5
MDL Number: MFCD00002494 Molecular Formula: C7H4Cl2O2 Molecular Weight: 191.01 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 187
Supplier:
Matrix Scientific
Description:
MF=C9H6F4O2 MW=222.14 Cas=238754-67-1 MDL=MFCD00236303 ,5G
Supplier:
Strem Chemicals Inc
Description:
Boronic Acid and Ester
Supplier:
AMBEED, INC
Description:
3,5-Diiodosalicylaldehyde 98%
Supplier:
AMBEED, INC
Description:
3,5-Diisopropylpyrazole 98%
Supplier:
AMBEED, INC
Description:
3,5-Dichloropyridine 98%
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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