Text Search >
L-Norvaline+ethyl+ester+hydrochloride
Print…
You Searched For:
0 results were found
L-Norvaline+ethyl+ester+hydrochloride
Supplier:
Adipogen
Description:
Verapamil hydrochloride is an alpha-adrenergic receptor (alpha-AR) antagonist and calcium channel protein inhibitor that blocks the L-type Ca2+ channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to reduce the renal clearance of digoxin and induce apoptosis in primary and metastatic colon adenocarcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as Mdr (P-glycoprotein). Verapamil is a substrate of CYP3A4 and CYP2C6. It is also used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342. Recent research has shown verapamil to be an effective treatment for diabetes in animal models. Verapamil helps treat diabetes by limiting TXNIP expression.
Catalog Number:
(101411-042)
Supplier:
Electron Microscopy Sciences
Description:
Brown and Brenn Method reagent for Gram Positive and Gram Negative Bacteria
Supplier:
AMBEED, INC
Description:
(9H-Fluoren-9-yl)methyl piperazine-1-carboxylate hydrochloride, Purity: 98%, CAS Number: 215190-22-0, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 25G
Supplier:
Bachem Americas
Description:
Sequence: H-Lys(Boc)-OMe · HCl
Supplier:
Spectrum Chemicals
Description:
Dimethylamine Hydrochloride, purity: 98 %, CAS number: 506-59-2, Molecular Formula: C2H7N.HCl, Molecular weight: 81.55, Form: Solid, synonyms: Hydrochloric acid dimethylamine, Methanamine, N-methyl-, hydrochloride, Dimethylammonium chloride, size: 500 g
Supplier:
Matrix Scientific
Description:
MF=C10H13N MW=147.22 CAS=207451-81-8 MDL=MFCD03004622 5G
Catalog Number:
(101811-690)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 021278-500MG , MDL Number: MFCD00035504
Catalog Number:
(101840-120)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 035814-500MG , MDL Number: MFCD08701362
Catalog Number:
(77692-332)
Supplier:
LGC STANDARDS
Description:
1-Methyl-4-(phenylmethyl)piperazine Hydrochloride 1.0 mg/ml in Methanol (as free base), LoGiCal, LGC Standards
Catalog Number:
(76482-336)
Supplier:
AAT BIOQUEST INC
Description:
MCLA has been used to assess superoxide formation in a variety of conditions, including neutrophil and macrophage activation, cultured cells and vascular tissue.
Catalog Number:
(102834-844)
Supplier:
Matrix Scientific
Description:
3-Methylisothiazol-5-amine hydrochloride ≥97%
Catalog Number:
(77692-587)
Supplier:
LGC STANDARDS
Description:
1,2,3,4-Tetrahydro-4,6-dihydroxy-2-methyl-isoquinoline Hydrochloride, Mikromol, LGC Standards
Catalog Number:
(10397-452)
Supplier:
Bioss
Description:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
Catalog Number:
(10397-456)
Supplier:
Bioss
Description:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
Catalog Number:
(77415-646)
Supplier:
APOLLO SCIENTIFIC
Description:
1-[(Ammoniooxy)methyl]-2-chloro-4-fluorobenzene chloride 95%
Catalog Number:
(80055-494)
Supplier:
MilliporeSigma
Description:
A derivative of papaverine that blocks Ca2+ channels (principally the L-type) in smooth and cardiac muscle cells
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
|
|||||||||
List View
