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1,1\\\'-Binaphthyl-2,2\\\'-diyl+hydrogen+phosphate
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1,1\\\'-Binaphthyl-2,2\\\'-diyl+hydrogen+phosphate
Catalog Number:
(10364-146)
Supplier:
Bioss
Description:
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
Catalog Number:
(10297-698)
Supplier:
Bioss
Description:
Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1–8). GPx-1 plays an important role in the antioxidant defense of the vascular wall and neural cells in response to oxidative stress. GPx-2 is the major isoform in the lungs and its basal or inducible expression is dependent on Nrf2. GPx-3 is under regulation by hypoxic stress and the expression and deficiency of GPx-3 is associated with cardiovascular disease and stroke. GPx-5 is selenium-independent; it is bound to the acrosome of sperm, where it may protect sperm from premature acrosome reaction in the epididymis.
Catalog Number:
(10486-216)
Supplier:
Bioss
Description:
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Catalog Number:
(76109-226)
Supplier:
Bioss
Description:
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Catalog Number:
(RL013-0005)
Supplier:
Rockland Immunochemical
Description:
1mg. Antibody Concentration: 1 mg/mL. Fluorochrome/Protein: 1 mole TRITC per mole of Sheep IgG Fab. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: 10 mg/mL BSA, IgG and protease free. Lyophilized.
Catalog Number:
(10752-208)
Supplier:
Prosci
Description:
Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. NOX1 have the potential to be effective treatments for a range of ischemic diseases.
Catalog Number:
(100504-260)
Supplier:
Electron Microscopy Sciences
Description:
(Safranin T, Y or A; Basis Red 2; Cotton Red; Gossypimine)
C20H19N4Cl F.W. 350.85
Solubility: 4.5% Water; 3.5% Alcohol; 5.0% Cellosolve; 3.5% Glycol; 0.0% XylenePrussian Blue method for hemosiderin. Weigert's iron hematoxylin with methachromic dyes which stain nuclei and granules. A alkaline phosphate stain. Flemming's method for staining chromatin and nuclear elements.
Certified by the Biological Stain Commission All Dyes/Stains are for research use only. Not meant for drug, food household use.
Catalog Number:
(10402-110)
Supplier:
Bioss
Description:
Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
Catalog Number:
(95021-012)
Supplier:
HiMedia
Description:
For toxin detection in food products when <i>Clostridium botulinum</i> is suspected.
Catalog Number:
(10801-750)
Supplier:
Rockland Immunochemical
Description:
Anti-Glycerol Kinase antibody recognizes the phosphotransferase enzyme glycerol kinase. Glycerol kinase catalyzes the formation of glycerol phosphate by transferring a phosphate from ATP to glycerol. Dihydroxyactone and L-glycerladehyde can also act as acceptors in place of glycerol.
Anti-Glycerol Kinase is ideal for investigators interested in Cancer, Metabolism, and Kinase/Phosphatase enzymology.
Supplier:
BeanTown Chemical
Description:
CAS: 63-37-6; EC No: 200-556-6; MDL No: MFCD00006544
Crystalline; Molecular Formula: C9H14N3O8P; MW: 323.20
Melting Point: 222° (decomposes)
Supplier:
New England Biolabs (NEB)
Description:
A thermotolerant variant of T4 DNA Ligase, Hi-T4 DNA Ligase catalyzes the formation of a phosphodiester bond between juxtaposed 5 phosphate and 3 hydroxyl termini in duplex DNA or RNA and is designed to function at higher temperatures than wild type T4 DNA Ligase.
Catalog Number:
(76422-446)
Supplier:
Biolegend
Description:
CD127, Monoclonal Antibody, Clone: S18006K, Host: Rat, Species Reactivity: Mouse, Isotype: IgG, Immunogen: mouse IL7R-transfectants, Other Names: IL-7 receptor A chain, IL-7RA, Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide, Size: 500 uG
Catalog Number:
(10103-486)
Supplier:
Prosci
Description:
SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified.
Catalog Number:
(10392-128)
Supplier:
Bioss
Description:
KHK encodes the gene ketohexokinase that catalyzes conversion of fructose to fructose 1 phosphate. The splice variant presented encodes the highly active form found in liver, renal cortex, and small intestine, while the alternate variant encodes the lower activity form found in most other tissues.
Catalog Number:
(200064-420)
Supplier:
New England Biolabs (NEB)
Description:
9°N™ DNA Ligase catalyzes the formation of a phosphodiester bond between juxtaposed 5´ phosphate and 3´ hydroxyl termini of two adjacent oligonucleotides which are hybridized to a complementary target DNA
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is still displayed and you need assistance, please call us at 1-800-932-5000.
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