2-[Bis(2-hydroxyethyl)amino]ethanesulphonic+acid
Catalog Number:
(75924-316)
Supplier:
Biotium
Description:
This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Deoxyribonucleic acid (DNA) is a nucleic acid that stores long-term information regarding the development and function of all known living organisms. DNA consists of two long nucleotide polymers, which are composed of four bases, namely adenine, thymine, guanine and cytosine, all of which are flanked by a phosphate-deoxyribose backbone. Normally, DNA exists as a double-stranded (ds) molecule that forms in the shape of a double helix, allowing the bases and the backbone of the two strands to interact, thus forming a polynucleotide. When the double helix is unwound (either by enzymes or heat), DNA exists as a single-stranded (ss) molecule that is less stable than the double helix, but is necessary for protein access to DNA bases. Double stranded DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.
Supplier:
Biotium
Description:
This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Deoxyribonucleic acid (DNA) is a nucleic acid that stores long-term information regarding the development and function of all known living organisms. DNA consists of two long nucleotide polymers, which are composed of four bases, namely adenine, thymine, guanine and cytosine, all of which are flanked by a phosphate-deoxyribose backbone. Normally, DNA exists as a double-stranded (ds) molecule that forms in the shape of a double helix, allowing the bases and the backbone of the two strands to interact, thus forming a polynucleotide. When the double helix is unwound (either by enzymes or heat), DNA exists as a single-stranded (ss) molecule that is less stable than the double helix, but is necessary for protein access to DNA bases. Double stranded DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.
Supplier:
Biolegend
Description:
APC anti-mouse/rat XCR1 [ZET]; Isotype: Mouse IgG2b, κ; Reactivity: Mouse, Rat; Apps: FC; Size: 100 μg
Catalog Number:
(76194-686)
Supplier:
Prosci
Description:
Recognizes a 485 amino acid protein (55 kDa monomer / 110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyzes the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.
Catalog Number:
(RL-612-1102)
Supplier:
Rockland Immunochemical
Description:
Anti-RAT IgG (H&L) (GOAT) Antibody is suitable for ELISA, Western Blot and Immunohistochemistry applications. Specific conditions for reactivity should be optimized by the end user.
Catalog Number:
(10294-712)
Supplier:
Bioss
Description:
May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity).
Catalog Number:
(75929-548)
Supplier:
Rockland Immunochemical
Description:
PTPRF or leukocyte common antigen-related protein (LAR) is a widely expressed protein tyrosine phosphatase with an extracellular receptor region that resembles a cell adhesion molecule. PTPRF removes phosphate group from β-catenin, an event that may subsequently facilitate cell-cell adhesion and ensure the stability of the cadherin complex. This phosphatase has also been implicated in various cellular processes such as neurite growth, nerve regeneration, actin remodeling and regulation of insulin function (1,2,3,4). Anti-PTPRF (C-terminal) antibody is specific for the extracellular and cytoplasmic subunits of human PTPRF (approx. 210, 150 and 85 kDa). Detection of the PTPRF bands by immunoblotting is specifically inhibited by the immunizing peptide. Anti-PTPRF is ideal for researchers interested in Cell adhesion Cadherin-mediated cell adhesion pathways, PAK pathways, insulin resistance and ureterocele.
Catalog Number:
(10281-220)
Supplier:
Bioss
Description:
Mitochondrial ATP synthases (ATPases) transduce the energy contained in membrane electrochemical proton gradients into the energy required for synthesis of high-energy phosphate bonds. ATPases contain two linked complexes: F1, the hydrophilic catalytic core; and F0, the membrane-embedded protein channel. F1 consists of three Alpha chains and three Beta chains, which are weakly homologous, as well as one Gamma chain, one Delta chain and one Gamma chain. F0 consists of three subunits: a, b and c. A mitochondrial F1-ATPase inhibitor protein, ATPIF1 (ATPase inhibitory factor 1), also known as IP, IF1, ATPI or ATPIP (ATPase inhibitor protein), binds to the C-terminal region of a Beta subunit of the F1-ATPase at low pH values and, via interference of the Beta and Gamma subunit interaction, ATPIF1 regulates the activity of the F1F0-ATPase. This reversible ATPIF1 binding to F1F0-ATPase also occurs on the surface of endothelial cells.
Catalog Number:
(10757-078)
Supplier:
Biolegend
Description:
Alexa Fluor® 594 anti-mouse Podoplanin [8.1.1]; Isotype: Syrian Hamster IgG; Reactivity: Mouse; Apps: IF, IHC-F; Size: 100 μg
Supplier:
Biolegend
Description:
Alexa Fluor® 647 anti-mouse/rat XCR1 [ZET]; Isotype: Mouse IgG2b, κ; Reactivity: Mouse, Rat; Apps: FC; Size: 100 μg
Catalog Number:
(10763-304)
Supplier:
Biolegend
Description:
Purified anti-T-bet (MaxPar® Ready) [4B10]; Isotype: Mouse IgG1, κ; Reactivity: Human, Mouse; Apps: WB, CyTOF®; Size: 100 μg
Catalog Number:
(RL100-1156)
Supplier:
Rockland Immunochemical
Description:
This purified antibody has been tested for use in ELISA, immunofluorescence microscopy and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 48 kDa in size.
Supplier:
Alconox
Description:
Luminox is a neutral pH detergent for use in manual, ultrasonic, and machine cleaning. Safe-handling detergent used for non-corrosive cleaning without chelation or alkalinity waste treatment problems. Recommended for residue free cleaning of aluminum and soft metal, medical devices, pharmaceutical equipment, alkaline sensitive labware, and medical instruments in aluminum trays. Free rinsing, eliminating interfering residues.
Catalog Number:
(RL202-4307)
Supplier:
Rockland Immunochemical
Description:
This product has been assayed against 1.0 µg of Cat IgM in a standard capture ELISA using ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid])
Supplier:
Biolegend
Description:
PerCP/Cy5.5 anti-mouse CD47 [miap301]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: FC; Size: 100 μg
Catalog Number:
(RL610-709-002)
Supplier:
Rockland Immunochemical
Description:
Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring lot-to-lot consistency.
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