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2\\\'-Deoxyguanosine+hydrate
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2\\\'-Deoxyguanosine+hydrate
Catalog Number:
(76198-900)
Supplier:
Genscript
Description:
The product is specific for human PD-L1 (UniProt Accession: Q9NZQZ). This antibody blocks human PD-1 binding with human PD-L1 expression cell line in flow cytometry assay.
Catalog Number:
(PI26181)
Supplier:
Invitrogen
Description:
26181 is supplied as 2 ml of antibody on crosslinked 4% beaded agarose supplied as a 50% slurry in 0. 1M phosphate, 0. 15M NaCl, pH 7. 2 with 0. 05% sodium azide. Specific for the HA peptide YPYDVPDYA. The anti-HA agarose has been used successfully in immunoprecipitation applications. The anti-HA agarose has 3. 5mg mouse anti-HA IgG1 monoclonal antibody conjugated per mL of settled agarose resin. HA Synthetic Peptide is available for use in neutralization and control experiments and to competitively elute HA-tagged fusion proteins from immobilized anti-HA affinity resin. An HA tag is frequently incorporated into recombinant proteins for a variety of purposes. An anti-HA antibody can then be used to detect the protein when doing studies with transfected cells.
Catalog Number:
(102981-752)
Supplier:
Adipogen
Description:
Human CD326 is a 40kD glycoprotein expressed on epithelial cells and many carcinomas. It is an adhesion molecule whose function is implicated in carcinogenesis and erythropoesis. CD326 has great potential as a therapeutic and diagnostic marker for cancer.
Catalog Number:
(102981-746)
Supplier:
Adipogen
Description:
Human CD326 is a 40kD glycoprotein expressed on epithelial cells and many carcinomas. It is an adhesion molecule whose function is implicated in carcinogenesis and erythropoesis. CD326 has great potential as a therapeutic and diagnostic marker for cancer.
Catalog Number:
(RL614-4303)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG F(c) Reacts with Pig (Swine, Porcine)
Catalog Number:
(76010-922)
Supplier:
Prosci
Description:
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
Catalog Number:
(10278-266)
Supplier:
Bioss
Description:
The PHEX a 749 amino acid protein that putatively consists of an intracellular, transmembrane and extracellular domain. PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients. The PHEX protein, which is a single-pass membrane protein, is also designated HYP, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX. PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption. X-linked hypophosphatemic rickets, also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood.
Catalog Number:
(10269-028)
Supplier:
Bioss
Description:
Myo-inositol is involved in many important aspects of cellular regulation including membrane structure, signal transduction and osmoregulation. It is taken up into cells by the sodium/myo-inositol cotransporter (SMIT). SMIT activity maintains intracellular concentrations of myo-inositol; it is upregulated in response to hypertonic stress. The human SMIT protein is encoded by the SLC5A3 gene, which maps to chromosome 21q22.12. It is expressed in many human tissues, such as brain, kidney and placenta. Specifically, SMIT is abundantly expressed throughout the whole brain and spinal cord in fetal rat, but is downregulated in adult rat brain with the exception of the choroid plexus, where SMIT expression remains high. In kidney, SMIT localizes to the baso-lateral membranes of the thick ascending limb of Henle (TAL) and the inner medullary collecting duct (IMCD). Impaired SMIT activity is implicated in the pathogenesis of diabetes and Down syndrome.
Catalog Number:
(IC0856007)
Supplier:
MP Biomedicals
Description:
Product is the lyophilized powder of goat antiserum to swine serum and buffer salts.
Supplier:
HiMedia
Description:
Iscove’s Modified Dulbecco’s Medium is an enriched modification of Dulbecco’s Modified Eagle’s Medium wherein serum can be partially or totally replaced by chemically defined substances.
Catalog Number:
(10396-434)
Supplier:
Bioss
Description:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
Catalog Number:
(12001-120)
Supplier:
Lonza
Description:
AccuGENEâ„¢ Molecular Biology Buffers are ready-to-use solutions ideal for a wide range of molecular biology applications. Each reagent is prepared with 18 megOhm water, filtered using a 0.2 micron filter, and filled into sterile bottles.
Catalog Number:
(200012-626)
Catalog Number:
(RL610-4021)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG F(ab')2 Reacts with Mouse
Catalog Number:
(RL606-4003)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG F(c) Reacts with Guinea Pig
Supplier:
Biolegend
Description:
APC anti-mouse CD47 [miap301]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: FC; Size: 100 μg
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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