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Sodium+methotrexate
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Sodium+methotrexate
Supplier:
AMBEED, INC
Description:
Mupirocin ≥98%
Supplier:
ALADDIN SCIENTIFIC
Description:
Asperosaponin VI, A saponin component from Dipsacus asper wall, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway. Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB.
Supplier:
MP Biomedicals
Description:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites. Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis. Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.
Supplier:
TCI America
Description:
CAS Number: 104376-79-6
MDL Number: MFCD00941454 Molecular Formula: C18H18N8O7S3 Molecular Weight: 598.53 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 236 Specific rotation [a]20/D: -160 deg (C=1, H2O)
Catalog Number:
(77402-502)
Supplier:
APOLLO SCIENTIFIC
Description:
2-Acetylthiophene 97%
Supplier:
Enzo Life Sciences
Description:
Ceritinib is a selective inhibitor of ALK, a target found in metastatic non-small cell lung cancer.
Catalog Number:
(101935-634)
Supplier:
Matrix Scientific
Description:
MF=C15H24Cl2N2O2 MW=335.28 ,250Mg
Catalog Number:
(AAJ66364-MD)
Supplier:
Thermo Scientific Chemicals
Description:
Inhibits the metabolism of folic acid
Catalog Number:
(77569-300)
Supplier:
AMBEED, INC
Description:
Fmoc-(N-β-4-methyltrityl)-L-α,β-diaminopropionic acid 97%
Supplier:
AMBEED, INC
Description:
Clindamycin hydrochloride ≥98%
Supplier:
AMBEED, INC
Description:
(R)-(-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl-p-toluenesulfonate 97%
Catalog Number:
(TS34240-5000)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
(S)-(+)-Abscisic acid ≥98%
Supplier:
AMBEED, INC
Description:
ß-Nicotinamide adenine dinucleotide phosphate (NADP-Na<sub>2</sub>, oxidized form)
Supplier:
AMBEED, INC
Description:
Cefotiam dihydrochloride ≥98%
Catalog Number:
(89150-386)
Supplier:
Enzo Life Sciences
Description:
Fluoroquinolone with broad spectrum activity against Gram-negative and Gram-positive bacteria
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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