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2-(Phenoxymethyl)benzoic+acid
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2-(Phenoxymethyl)benzoic+acid
Catalog Number:
(103403-854)
Supplier:
Novus Biologicals
Description:
The B7-2 / CD86 Antibody (C86 / 1146) [FITC] from Novus Biologicals is a mouse monoclonal antibody to B7-2 / CD86. This antibody reacts with human, mouse, rat. The B7-2 / CD86 Antibody (C86 / 1146) [FITC] has been validated for the following applications: Flow Cytometry, Immunohistochemistry-Paraffin.
Catalog Number:
(103413-408)
Supplier:
Novus Biologicals
Description:
The AP2 alpha Antibody (AP2a 8G8 / 5) [FITC] from Novus Biologicals is a mouse monoclonal antibody to AP2 alpha. This antibody reacts with human. The AP2 alpha Antibody (AP2a 8G8 / 5) [FITC] has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.
Catalog Number:
(103404-724)
Supplier:
Novus Biologicals
Description:
The beta 2-Microglobulin Antibody (B2M / 961) [FITC] from Novus Biologicals is a mouse monoclonal antibody to beta 2-Microglobulin. This antibody reacts with human, primate. The beta 2-Microglobulin Antibody (B2M / 961) [FITC] has been validated for the following applications: Flow Cytometry, Immunohistochemistry-Paraffin.
Catalog Number:
(10471-042)
Supplier:
Bioss
Description:
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.
Catalog Number:
(10480-338)
Supplier:
Bioss
Description:
Guanine nucleotide exchange factor (GEF) for RAB35. May function as a clathrin-associated sorting protein for RAB35, whereby during clathrin-mediated endocytosis, binds the AP-2 complex and inactived RAB35, then activates RAB35 for its subsequent function at endosomes.Tissue specificity:Highly expressed in dendritic and natural killer cells and at lower levels in other myeloid lineage cells and in pituitary. Significantly up-regulated in effector memory T cells as compared with naive T cells.
Catalog Number:
(10665-084)
Supplier:
Bioss
Description:
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
Catalog Number:
(10469-358)
Supplier:
Bioss
Description:
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
Catalog Number:
(10449-368)
Supplier:
Bioss
Description:
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Sequence similarities Belongs to the heat shock protein 70 family.
Catalog Number:
(103396-826)
Supplier:
Novus Biologicals
Description:
The Cadherin-16 Antibody (CDH16 / 1071) [FITC] from Novus Biologicals is a mouse monoclonal antibody to Cadherin-16. This antibody reacts with human, mouse, rat, canine, rabbit. The Cadherin-16 Antibody (CDH16 / 1071) [FITC] has been validated for the following applications: Flow Cytometry, Immunohistochemistry-Paraffin.
Catalog Number:
(75843-690)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
Catalog Number:
(103404-006)
Supplier:
Novus Biologicals
Description:
The BAFF / BLyS / TNFSF13B Antibody (H4-C7) [FITC] from Novus Biologicals is a mouse monoclonal antibody to BAFF / BLyS / TNFSF13B. This antibody reacts with human, rat. The BAFF / BLyS / TNFSF13B Antibody (H4-C7) [FITC] has been validated for the following applications: ELISA.
Catalog Number:
(75842-212)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
Catalog Number:
(75842-530)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The GARP5 monoclonal antibody specifically reacts with human Glycoprotein A Repetitions Predominant (GARP, also known as LRRC32 or Garpin) molecule, a 80 kDa transmembrane glycoprotein expressed on the cell surface. GARP is expressed in activated Treg cells, placenta, pancreas, liver, skeletal muscle, heart, lung, and kidney, and it acts as a receptor for latent TGF-β, which down-regulates the Treg cells action.
Catalog Number:
(10405-804)
Supplier:
Bioss
Description:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Catalog Number:
(10336-626)
Supplier:
Bioss
Description:
The protein encoded by this gene is a cytokine that actsas a regulator of a variety of hematopoietic cells. This cytokinestimulates cell proliferation and prevents apoptosis. It functionsthrough the interleukin 9 receptor (IL9R), which activatesdifferent signal transducer and activator (STAT) proteins and thusconnects this cytokine to various biological processes. The geneencoding this cytokine has been identified as a candidate gene forasthma. Genetic studies on a mouse model of asthma demonstratedthat this cytokine is a determining factor in the pathogenesis ofbronchial hyperresponsiveness. [provided by RefSeq, Jul 2008].
Catalog Number:
(10455-784)
Supplier:
Bioss
Description:
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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