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1-(2,6-Dichloropyridin-4-yl)ethanone
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1-(2,6-Dichloropyridin-4-yl)ethanone
Supplier:
Adipogen
Description:
Kinases, such as LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2), have been identified as participating in signal pathways affecting actin dynamics by deactivating cofilin. Over expression of LMK1 has been found in invasive breast and prostate cancer cell lines and suppression of LIMK 2 expression has been found to limit migration of human fibrosarcoma cells. Thus, the inhibition of LIMK1 and/or LIMK2 enzymes have been suggested as targets for treating cancer, including reduction or prevention of metastasis. BMS-5 is a potent inhibitor of the LIM kinase. It has IC(50) values of 7nM and 8nM for LIMK1 and LIMK2 respectively. LIMK1/2 activity was measured via TCA precipitation assay using a biotinylated ADF (actin depolymization factor) as the protein substrate and the kinase domains of LIMK1 and LIMK2 as the enzyme sources in the presence of 1µM ATP.
Catalog Number:
(101937-400)
Supplier:
Matrix Scientific
Description:
MF=C14H23Bn2O3 MW=278.16 Cas=903550-26-5 ,25G
Supplier:
AMBEED, INC
Description:
Neryl acetate 95%
Supplier:
AMBEED, INC
Description:
5,6-Dichloropyridin-3-ol, Purity: 98%, CAS Number: 110860-92-9, Appearance: Form: Crystal - Powder/Colour: White - Slightly pale reddish yellow, Storage: Inert atmosphere, Room Temperature, Size: 1g
Catalog Number:
(10815-880)
Supplier:
Thermo Scientific Chemicals
Description:
Naringin dihydrochalcone, Purity: 98%, CAS Number: 18916-17-1, Formula: C27H34O14, Synonyms: 1-[4-[(2-O-(6-Deoxy-a-L-rhamnopyranosyl)-b-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, Form: Powder, Color: White to off-white, Size: 1G
Supplier:
AMBEED, INC
Description:
(S)-5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one, Purity: 97%, CAS: 520-26-3, Appearance: Crystal/Powder, Very pale yellow-Yellow, Size: 25G
Catalog Number:
(77313-600)
Supplier:
AMBEED, INC
Description:
4-(Thiazol-2-yl)aniline 95%
Catalog Number:
(77406-602)
Supplier:
APOLLO SCIENTIFIC
Description:
3-Imidazo[2,1-b]thiazol-6-ylphenylamine
Catalog Number:
(77685-112)
Supplier:
AMBEED, INC
Description:
CC-122 95%
Catalog Number:
(101841-640)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 036567-500MG , MDL Number: MFCD00006178
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 057417-25G , MDL Number: MFCD09750301
Catalog Number:
(TCD0411-025G)
Supplier:
TCI America
Description:
CAS Number: 2457-47-8
MDL Number: MFCD00006376 Molecular Formula: C5H3Cl2N Molecular Weight: 147.99 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 178 Melting point (°C): 65
Catalog Number:
(76910-728)
Supplier:
AOB CHEM USA
Description:
3-Bromo-2,4-dichloropyridine ≥97%
Supplier:
AMBEED, INC
Description:
Methyl 2-(6-chloropyridin-3-yl)acetate 97%
Catalog Number:
(AAAL19723-14)
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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