1-(4-Chloro-2,3-difluorophenyl)ethanol
Supplier:
AMBEED, INC
Description:
3-Chlorobenzene-1,2-diol, Purity: 95%, CAS Number: 4018-65-9, Appearance: Colorless or white to yellow solid or liquid or semi-solid, Storage: Inert atmosphere, Room Temperature, Size: 250mg
Supplier:
Adipogen
Description:
The BCR-ABL oncogene triggers intracellular signaling, activating multiple transduction cascades, promoting the growth, proliferation and survival of hematopoietic cells. BCR-ABL plays a role in defective DNA repair, alteration of cellular adhesion and inhibition of apoptosis. Degregulated BCR-ABL tyrosine kinase activity is the molecular marker for CML. Inhibiting BCR-ABL tyrosine kinase activity leads to the induction of apoptosis and inhibits cellular proliferation in vitro and there are various BCR-ABL isoforms with differing activity levels as well. Dasatinib (BMS-354825, Sprycel®) is a potent multi-target kinase inhibitor of BCR-ABL. Dasatiinib performs better against ABL kinase than earlier drugs such as imatinib, and Dasatinib also is effective against SRC family of kinases, and other receptor kinases such as EPHA2, PDGFR, and c-Kit. Dasatinib's inhibiting potential against Src family kinase members is greater (IC(50) 0.5nM) than its inhibitory activity against ABL (1nM).
Catalog Number:
(TCC1719-5G)
Supplier:
TCI America
Description:
CAS Number: 4857-06-1
MDL Number: MFCD00051944 Molecular Formula: C7H5ClN2 Molecular Weight: 152.58 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal
Catalog Number:
(89158-042)
Supplier:
Enzo Life Sciences
Description:
Potent and selective inhibitor of GSK-3β (IC50=78nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke.
Supplier:
AMBEED, INC
Description:
4-Chloro-7-azaindole 98%, Ambeed.Inc
Catalog Number:
(102835-942)
Supplier:
Matrix Scientific
Description:
3-(Aminomethyl)-5-chlorophenol ≥95%
Catalog Number:
(101795-290)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 008723-100G , MDL Number: MFCD00006241
Supplier:
TCI America
Description:
CAS Number: 3972-56-3
Molecular Formula: C10H13Cl Molecular Weight: 168.66 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 216 Freezing point (°C): 23
Catalog Number:
(TCC1112-10ML)
Supplier:
TCI America
Description:
CAS Number: 557-98-2
MDL Number: MFCD00000859 Molecular Formula: C3H5Cl Molecular Weight: 76.52 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 23 Flash Point (°C): -20 Specific Gravity (20/20): 0.90 Storage Temperature: 0-10°C
Supplier:
VWR International
Description:
Ethanol denatured ACS (denatured with 5% isopropanol and 5% methanol), VWR Chemicals BDH®
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Supplier:
AOB CHEM USA
Description:
4-(2,4-Difluorophenyl)pyridine 97
Supplier:
AMBEED, INC
Description:
2-(2,4-Difluorophenyl)pyridine 98%
Catalog Number:
(76877-588)
Supplier:
AMBEED, INC
Description:
2-(3,4-Difluorophenyl)oxirane 95%
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