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Boc-Cys(SEt)-OH\\\\u00B7DCHA
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Boc-Cys(SEt)-OH\\\\u00B7DCHA
Catalog Number:
(76101-540)
Supplier:
Bioss
Description:
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Doxepin-d3 HCl (Mixture of Z and E Isomer)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 053558-500MG , MDL Number: MFCD13562875
Catalog Number:
(10303-848)
Supplier:
Bioss
Description:
The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS. Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box. The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. During Th1 differentiation a reduction in the association of Jak1 with the IL4 Receptor correlated with the appearance of SOCS5. SOCS5 protein was preferentially expressed in committed Th1 cells and interacted with the cytoplasmic region of the IL4 Receptor alpha chain irrespective of receptor tyrosine phosphorylation. This unconventional interaction of SOCS5 protein with IL4 Receptor resulted in the inhibition of IL4-mediated signal transducer and activator of transcription-6 activation. T cells from transgenic mice constitutively expressing SOCS5 exhibited a significant reduction of IL4-mediated Th2 development. Therefore, the induced SOCS5 protein in Th1 differentiation environment may play an important role by regulating Th1 and Th2 balance.
Supplier:
MP Biomedicals
Description:
DL-Dithiothreitol is a Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH). In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution. Disulfide reduction occurs quickly at pH 8.
Supplier:
HCL Label
Description:
HCL's no copper labels are adhesive vinyl, double-bagged and cleanroom ready.
Catalog Number:
(75789-920)
Supplier:
Prosci
Description:
Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils), and found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain and so on. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It also binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Catalog Number:
(76548-218)
Supplier:
StatLab
Description:
A uniquely formulated hematoxylin stain that can be used in place of Gill or Harris hematoxylins.
Supplier:
AMBEED, INC
Description:
DL-Alanine methyl ester hydrochloride 98%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052579-2.5G , MDL Number: MFCD13562313
Supplier:
Bachem Americas
Description:
Sequence: H-Abu-OMe · HCl
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
DL-Histidine monohydrochloride monohydrate 98%
Supplier:
Bachem Americas
Description:
Sequence: H-allo-Thr-OMe · HCl
Supplier:
BeanTown Chemical
Description:
CAS: 1119-34-2; EC No: 214-275-1; MDL No: MFCD00064550; RTECS: CF1995500
Powder; Molecular Formula: C6H14N4O2·HCl; MW: 210.66
Optical Rotation: [α]20/D +22.0±0.5°, c = 5% in 5M HCl
Hygroscopic
Supplier:
Bachem Americas
Description:
Sequence: Z-Lys-ONp · HCl
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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