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1-Azetidinesulfonyl+chloride
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1-Azetidinesulfonyl+chloride
Catalog Number:
(75928-306)
Supplier:
Rockland Immunochemical
Description:
Guinea Pig IgG F(ab')2 Fragment
Catalog Number:
(10247-198)
Supplier:
Bioss
Description:
Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
Catalog Number:
(RLP100-0005)
Supplier:
Rockland Immunochemical
Description:
Primary Goat Anti-Peroxidase (PAP) Soluble Complex Reacts with N/A
Supplier:
Adipogen
Description:
Sulforhodamine 101 is a non-fixable red fluorescent dye used as a specific marker for astrocytes and an activity-dependent probe for monitoring regulated exocytosis. In addition to labeling astrocytes, it also labels myelinating oligodendrocytes. Has been reported to affect excitability of neurons and should therefore be used with caution. Key precursor used for preparing rhodamine 101 sulfonyl chloride (also called Texas Red). Spectral data: lambdaex 586 nm| lambdaem 605 nm in H2O and lambdaex 582-588 nm| lambdaem 601-609 nm in pH7 buffer.
Catalog Number:
(76194-696)
Supplier:
Prosci
Description:
Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
Catalog Number:
(10430-698)
Supplier:
Bioss
Description:
Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.
Catalog Number:
(RLP500-0005)
Supplier:
Rockland Immunochemical
Description:
Primary Sheep Anti-Peroxidase (PAP) Soluble Complex Reacts with N/A
Catalog Number:
(RL208-4107)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgM mu chain Reacts with Horse (Equine)
Catalog Number:
(RL113-4107)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgM mu chain Reacts with Sheep (Ovine)
Catalog Number:
(10306-080)
Supplier:
Bioss
Description:
The calcium-activated chloride channel (CLCA) protein family, which includes the human homologs CLCA1 and CLCA2, display distinct tissue distribution patterns. CLCA1 is expressed as a precursor protein that is processed into two cell surface associated subunits and a group of proteins. CLCA1 is upregulated by interleukin-9 and regulates the expression of mucins. CLCA1 may provide a therapeutic target to control mucus overproduction in airway disease patients with cystic fibrosis. CLCA2 expression is downregulated in breast cancer, therefore CLCA2 is thought to act as a tumor suppressor in normal cells. CLCA3 (known as Clca3 in mouse) is a structurally divergent member of the CLCA family that does not function as a channel protein. CLCA4 is a CLCA member that is expressed in human rectal mucosa, CLCA5 shows strong expression in eye and spleen, and CLCA6 is primarily expressed in intestine and stomach.
Catalog Number:
(RL710-4920)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG (H&L) Reacts with Mouse
Catalog Number:
(RL203-1150)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgY (H&L) Reacts with Chicken
Catalog Number:
(RL607-1002)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgG (H&L) Reacts with Hamster
Catalog Number:
(RL605-709-002)
Supplier:
Rockland Immunochemical
Description:
Secondary Donkey Anti-IgG (H&L) Reacts with Goat
Catalog Number:
(RL610-602-002)
Supplier:
Rockland Immunochemical
Description:
Secondary Sheep Anti-IgG (H&L) Reacts with Mouse
Catalog Number:
(RL607-1202)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgG (H&L) Reacts with Hamster
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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