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12-Deoxyphorbol-13-acetate
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12-Deoxyphorbol-13-acetate
Catalog Number:
(10278-014)
Supplier:
Bioss
Description:
Hemogen is a 484 amino acid protein encoded by the human gene HEMGN. Hemogen is a nuclear protein that is expressed in hematopoietic precursor cells and can be detected in CD34+ and K-562 leukemia cell line. It is also expressed in bone marrow, testis, thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. Hemogen is down-regulated during megakaryocytic differentiation of K-562 cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) (at protein level). It can be up-regulated in normal PBMCs by mitogens.
Catalog Number:
(10782-434)
Supplier:
Biosensis
Description:
The Bcl-2 family of proteins which regulate apoptosis share identical sequences called Bcl-2 Homology domains (BH1-4). The BH3 proteins, including BID, NOXA, PUMA, BIK, BIM and BAD are all pro-apoptotic and share sequence identity within the amphipathic alpha-helical BH3 region, which is essential for their apoptotic function. NOXA is highly expressed in adult T-cell leukemia cell line.
Supplier:
BDH
Description:
Meets reagent specifications for testing USP/NF monographs.
Catalog Number:
(10782-432)
Supplier:
Biosensis
Description:
The Bcl-2 family of proteins which regulate apoptosis share identical sequences called Bcl-2 Homology domains (BH1-4). The BH3 proteins, including BID, NOXA, PUMA, BIK, BIM and BAD are all pro-apoptotic and share sequence identity within the amphipathic alpha-helical BH3 region, which is essential for their apoptotic function. NOXA is highly expressed in adult T-cell leukemia cell line.
Supplier:
Bachem Americas
Description:
Lanreotide, a cyclic somatostatin agonist shows a high binding affinity for the somatostatin receptor (SSTR) subtype 2 and has a 10-fold less affinity for receptor subtype 5. It is also a potent inhibitor of growth hormone secretion from pituitary cells. Furthermore, the octapeptide exhibits a direct antiproliferative effect in vivo and in vitro on the growth of cells or solid tumors from a human small cell lung carcinoma. CAS Number (lanreotide acetate): 127984-74-1. Offered under Bolar Exemption: All APIs that are sold for development of drug products still patent protected are offered under Bolar Exemption only. The following disclaimer applies: These products are offered and sold in small quantities only and solely for uses reasonably related to privileged trials and studies for obtaining marketing authorization required by law (Bolar Exemption). Bachem cannot be made liable for any infringement of intellectual property rights. It is the sole and only responsibility of the purchaser or user of these products to comply with the relevant national rules and regulations.
Catalog Number:
(BDH9232-500G)
Catalog Number:
(89367-202)
Supplier:
Genetex
Description:
Recently a BH3 only member of the Bcl2 family has been identified in human and mouse and designated as Noxa (for damage). The expression of the Noxa gene involves direct activation of its promoter by p53. Increased expression of Noxa protein occurs in normal thymocytes but not in p53 deficient thymocytes. Noxa cDNA codes for a 103 amino acid protein. The co-immunoprecipitation data suggest that Noxa protein may interact with proteins belonging to the Bcl2 family, such as, BclXL and Mcl1. It has also been shown that blocking the endogenous Noxa induction results in the suppression of apoptosis. Treatment of cells with Noxa antisense oligonucleotides blocks radiation induced apoptosis suggesting that Noxa may represent a mediator of p53 dependent apoptosis.
Supplier:
VWR International
Description:
Suitable as a titrant. Made with deionized water.
Supplier:
AMBEED, INC
Description:
Sodium 2-(1,3-benzothiazol-2-yl)acetate 95%
Supplier:
APOLLO SCIENTIFIC
Description:
2-[5-Methyl-2-(2-thienyl)-1,3-thiazol-4-yl]acetic acid 95%
Supplier:
AMBEED, INC
Description:
Ethyl-2-(2-methyl-1,3-dioxolan-2-yl)acetate 98%
Supplier:
Matrix Scientific
Description:
(1,3-Dioxolan-2-yl)acetic acid methyl ester
Supplier:
AMBEED, INC
Description:
Methyl-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetate 98%
Supplier:
AMBEED, INC
Description:
2-((1,3-Dioxoisoindolin-2-yl)oxy)acetic acid ≥97%
Catalog Number:
(101926-006)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 063584-500MG , MDL Number: MFCD00023083
Catalog Number:
(101920-362)
Supplier:
Matrix Scientific
Description:
[2-(2-Ethylpyridin-4-yl)-1,3-thiazol-4-yl]acetic acid hydrochloride
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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