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2,2\'-Dihydroxy-4-methoxybenzophenone
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2,2\'-Dihydroxy-4-methoxybenzophenone
Catalog Number:
(77440-004)
Supplier:
Bioss
Description:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis, metastasis, and atherosclerosis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.<br> MMP12 was first described in murine macrophages, later in human macrophages, and more recently in other cell types. Also known as metalloelastase, MMP12 is able to degrade elastin, entactin, laminin 1, fibronectin, type IV collagen as well as insulin B-chain and casein. MMP12 is often confused with the Serine proteinase, Leukocyte elastase (EC 3.4.21.37) because of similar nomenclature. MMP12 is structurally similar to the classical MMPs (MMP1, MMP3); it contains a propeptide with autoinhibitory cysteine switch site, a well-conserved zinc site, hinge region and hemopexin domain. MMP12 lacks a transmembrane domain and furin cleavage site. The zymogen for MMP-12 is about 54 kD, and is quickly activated to the 45 kD form; and this breaks down to cascade of active forms, ending with the common 22 kD form. Stimulated macrophages produce MMP12; it has also been found in osteosarcoma cells, synovial fibroblasts and lung fibroblasts.
Catalog Number:
(77892-851)
Supplier:
AMBEED, INC
Description:
34-DIHYDROXY-5-NITROBENZOIC ACID 25G
Catalog Number:
(77886-637)
Supplier:
AMBEED, INC
Description:
METHYL 14-DIHYDROXY-2-NAPHTHOATE 100G
Catalog Number:
(77947-662)
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
DELTA-14-ACETOPHENIDE DIHYDROXY-50MG
Catalog Number:
(103783-416)
Supplier:
Avanti Polar Lipids Inc
Description:
7A27-DIHYDROXY-4-CHOLESTEN-3-ONE 1MG
Catalog Number:
(77947-660)
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
DELTA-14-ACETOPHENIDE DIHYDROXY-10MG
Supplier:
VWR
Description:
Anionic - negatively-charged (carboxylates, sulfates or sulfonates in alkali metal form). Utilized for applications ranging from solubilizing membrane proteins in non-denaturing conditions to creating denaturing conditions during gel electrophoresis. Used for complete disruption of membranes.
Catalog Number:
(103652-786)
Supplier:
Matrix Scientific
Description:
3 6-DIHYDROXY-XANTHEN-9-ONE 95%+ 1G
Catalog Number:
(103626-162)
Supplier:
Matrix Scientific
Description:
SODIUM 3 4-DIHYDROXY-9 10-D 099680-100G
Catalog Number:
(77879-412)
Supplier:
AMBEED, INC
Description:
37-DIHYDROXY-2-NAPHTHOIC ACID 5G
Catalog Number:
(77891-824)
Supplier:
AMBEED, INC
Description:
METHYL 34-DIHYDROXY-2-METHYLBENZOATE 25G
Catalog Number:
(103783-426)
Supplier:
Avanti Polar Lipids Inc
Description:
3B7A-DIHYDROXY-5-CHOLESTENOIC ACID 1MG
Catalog Number:
(BDH2033-1GLP)
Catalog Number:
(10863-274)
Supplier:
VWR International
Description:
This fast-acting, alcoholic counterstain stains erythrocytes, collagen, and the cytoplasm of muscle (epithelial cells) different shades of pink
Catalog Number:
(10108-522)
Supplier:
Prosci
Description:
GNB1L is a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. Therefore, this gene may contribute to the etiology of those disorders.This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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