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4-Chloro-3-methoxybenzonitrile
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4-Chloro-3-methoxybenzonitrile
Catalog Number:
(10235-536)
Supplier:
Bioss
Description:
Inhibitor of the caspase-activated DNase (DFF40).
Catalog Number:
(76293-156)
Supplier:
Cayman Chemical Company
Description:
An active, pure human recombinant enzyme.
Catalog Number:
(10399-974)
Supplier:
Bioss
Description:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Catalog Number:
(10399-972)
Supplier:
Bioss
Description:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Catalog Number:
(10399-970)
Supplier:
Bioss
Description:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Catalog Number:
(10421-618)
Supplier:
Bioss
Description:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Catalog Number:
(10399-968)
Supplier:
Bioss
Description:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Catalog Number:
(10402-500)
Supplier:
Bioss
Description:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Catalog Number:
(10421-616)
Supplier:
Bioss
Description:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Catalog Number:
(10421-622)
Supplier:
Bioss
Description:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Catalog Number:
(10473-352)
Supplier:
Bioss
Description:
ABHD14B has hydrolase activity towards p-nitrophenyl butyrate (in vitro). It may activate transcription. There are 2 isoforms produced by alternative splicing.
Catalog Number:
(10109-700)
Supplier:
Prosci
Description:
CCPG1 acts as an assembly platform for Rho protein signaling complexes. It limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. It does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42. It may be involved in cell cycle regulation.
Catalog Number:
(103007-070)
Supplier:
Anaspec Inc
Description:
Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.
This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity. Sequence:Ac-KQKLR-AMC MW:871.1 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(10323-596)
Supplier:
Bioss
Description:
Calpain, and m calpain, also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity (thus the mu) as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 and 2 are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. The calpains have papain like activity, thus the pain nomenclature. Both Calpain 1 and Calpain 2 are ubiquitously expressed, and are countered by the endogenous calpain inhibitor, calpastatin. Other calpain family members (calpain 94, ncl2, ncl3, etc) have more limited tissue distribution, and perhaps different functions. The calpain family members consist of a common small subunit (Calpain 4), and a large variable subunit. It is not clear that all calpains contain a small subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
Catalog Number:
(10231-748)
Supplier:
Bioss
Description:
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
Catalog Number:
(10231-754)
Supplier:
Bioss
Description:
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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